School of Veterinary Medicine, University of Surrey, Guildford, United Kingdom.
Animal Blood Bank, Porto, Portugal.
J Vet Intern Med. 2024 Nov-Dec;38(6):3050-3062. doi: 10.1111/jvim.17215. Epub 2024 Oct 12.
Feline blood transfusion is required for the treatment of various illnesses in cats, and the safety of donor cats is vital. Donor adverse reactions can include cardiorespiratory, venepuncture-related, and behavioral abnormalities.
HYPOTHESIS/OBJECTIVES: To describe a large number of feline blood donation events and document use of sedation and anxiolysis, record volume of blood collected and describe the frequency, type, and risk factors for, adverse reactions.
The study included 7812 individual cats and 29 201 donation events at a blood banking center over 5 years.
Retrospective analysis of donation event records with signalment, donation volume, sedation status, donation number, and adverse reactions (acute and caregiver reported) recorded. Risk factors for adverse reactions were examined by stratifying data according to groups exposed to relevant predictors and calculating odds ratios with 95% and 99% confidence intervals (CIs).
Adverse reactions were uncommon (0.29%, 2.88/1000 donor events) and most commonly were cardiorespiratory (0.08%, 0.75/1000 donor events) or behavioral (0.06%, 0.62/1000 donor events). The only risk factor significantly associated with adverse reactions was conscious donation, with conscious donors 4.4 times more likely to have an adverse reaction (95% CI, 2.5-7.9, P ≤ .0001).
Feline blood donation is associated with a low rate of adverse reactions. Sedation should be considered to reduce adverse reactions, and the environment and interactions optimized to reduce donor stress. Caregiver education on care postdonation could reduce behavioral adverse reactions.
猫科动物血液输注是治疗猫科动物各种疾病的必需手段，供体猫的安全性至关重要。供体的不良反应可能包括心肺、静脉穿刺相关和行为异常。
假设/目的：描述大量猫科动物献血事件，并记录镇静和抗焦虑的使用情况，记录采集的血量，并描述不良反应的频率、类型和危险因素。
本研究包括 5 年内血液银行中心的 7812 只个体猫和 29201 次献血事件。
对献血事件记录进行回顾性分析，记录了特征、献血量、镇静状态、献血次数和（急性和护理人员报告的）不良反应。根据暴露于相关预测因素的组分层数据，并计算优势比（95%和 99%置信区间），检查不良反应的危险因素。
不良反应并不常见（0.29%，2.88/1000 次献血事件），最常见的是心肺（0.08%，0.75/1000 次献血事件）或行为（0.06%，0.62/1000 次献血事件）。唯一与不良反应显著相关的危险因素是有意识的献血，有意识的献血者发生不良反应的可能性是无意识献血者的 4.4 倍（95%CI，2.5-7.9，P ≤ .0001）。
猫科动物血液捐献与不良反应发生率低相关。应考虑镇静以减少不良反应，并优化环境和互动以减少供体压力。对护理人员进行献血后护理教育可以减少行为不良反应。
