Department of Clinical Neuroscience and Therapeutics, Hiroshima University Graduate School of Biomedical and Health Sciences, Hiroshima, Japan.
Department of Rehabilitation Medicine, Hiroshima University Hospital, Hiroshima, Japan.
J Neurol Sci. 2024 Nov 15;466:123266. doi: 10.1016/j.jns.2024.123266. Epub 2024 Oct 4.
High-density surface electromyography (HD-sEMG) allows non-invasive analysis of motor unit (MU) activity and recruitment. This study examines MU recruitment features as well as action potential using HD-sEMG in the suprahyoid muscles of patients with Parkinson's disease (PD) and assesses alterations caused by cervical percutaneous interferential current stimulation.
Electrical activity of the suprahyoid muscles during tongue elevation was measured using HD-sEMG. Maximum voluntary contraction (MVC) was measured, then the modified entropy, coefficient of variation, correlation coefficient, and root mean square (RMS) were examined. For comparison, HD-sEMG was also conducted on healthy controls. In addition, this study assessed the impact of cervical percutaneous interferential current stimulation on HD-sEMG in patients with PD (Hoehn-Yahr stages 2-4) over 8 weeks.
Twenty-two patients with PD (mean age 71.7 ± 6.0, 7 females) and 14 healthy controls (mean age 74.9 ± 6.1, 7 females) were included. The RMS at 60 % MVC was significantly lower in patients with PD than in healthy controls (p = 0.007). After cervical percutaneous interferential current stimulation, the correlation coefficients at 40 % and 60 % MVC significantly decreased (p = 0.040 and p = 0.048, respectively), and the RMS at 60 % MVC significantly increased (p = 0.035).
HD-sEMG of the suprahyoid muscles showed characteristic findings in patients with PD and was able to detect subtle changes due to electrical stimulation intervention. Thus, HD-sEMG could be a promising tool for evaluating swallowing-related muscle conditions and interventions.
高密度表面肌电图（HD-sEMG）可实现对运动单位（MU）活动和募集的非侵入性分析。本研究使用 HD-sEMG 检查帕金森病（PD）患者颏舌骨肌的 MU 募集特征和动作电位，并评估颈经皮干扰电刺激引起的变化。
使用 HD-sEMG 测量舌抬高时颏舌骨肌的电活动。测量最大自主收缩（MVC），然后检查修正熵、变异系数、相关系数和均方根（RMS）。为了比较，还对健康对照组进行了 HD-sEMG 检查。此外，本研究还评估了颈经皮干扰电刺激对 8 周内 2-4 期 PD 患者 HD-sEMG 的影响。
共纳入 22 例 PD 患者（平均年龄 71.7±6.0 岁，7 名女性）和 14 名健康对照者（平均年龄 74.9±6.1 岁，7 名女性）。PD 患者的 60%MVC 时 RMS 明显低于健康对照组（p=0.007）。颈经皮干扰电刺激后，40%和 60%MVC 时的相关系数显著降低（p=0.040 和 p=0.048），60%MVC 时的 RMS 显著升高（p=0.035）。
颏舌骨肌的 HD-sEMG 在 PD 患者中表现出特征性发现，并能够检测到电刺激干预引起的细微变化。因此，HD-sEMG 可能是评估吞咽相关肌肉状况和干预措施的有前途的工具。
