Department of Dermatology, Nippon Medical School, Tokyo, Japan.
Department of Dermatology, Nippon Medical School Chiba Hokusoh Hospital, Chiba, Japan.
Med. 2024 Oct 11;5(10):1203-1205. doi: 10.1016/j.medj.2024.08.009.
Chronic hand eczema is a fluctuating, inflammatory, pruritic disease of the hands and wrists that is commonly treated with topical corticosteroids and emollients. In a recent report in The Lancet, Bissonnette et al. demonstrated that delgocitinib cream showed superior efficacy versus a cream vehicle and was well tolerated over 16 weeks in adults with moderate to severe chronic hand eczema.
慢性手部湿疹是一种手部和腕部的炎症性、瘙痒性疾病,通常采用局部皮质类固醇和保湿剂治疗。在最近发表在《柳叶刀》上的一篇报告中,Bissonnette 等人表明,delgocitinib 乳膏在 16 周的治疗中显示出优于乳膏载体的疗效,并且在治疗中度至重度慢性手部湿疹的成人患者中具有良好的耐受性。