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血清白蛋白水平与急性冠脉综合征经皮冠状动脉介入治疗后住院时间的关系。

Relationship between serum albumin level and hospitalization duration following percutaneous coronary intervention for acute coronary syndrome.

机构信息

Department of Cardiology, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, No. 3002, Sungang West Road, Futian District, Shenzhen, 518035, China.

Shenzhen University Health Science Center, Shenzhen, 518060, China.

出版信息

Sci Rep. 2024 Oct 12;14(1):23883. doi: 10.1038/s41598-024-74955-8.

Abstract

Low serum albumin levels increase coronary morbidity, mortality, and postoperative cardiovascular risk. Therefore, this study investigated the relationship between these levels and the length of hospital stay in patients undergoing percutaneous coronary intervention (PCI) for acute coronary syndrome. A total of 350 patients were divided into quartiles according to serum albumin levels. Univariate and multivariate analyses were performed to identify factors associated with the length of hospital stay. A non-linear regression analysis of serum albumin and length of hospital stay was also performed. The results of the multifactorial analysis revealed low serum albumin levels as an independent predictor of longer hospital stay, even in the fully adjusted model. In the segmented linear regression model, serum albumin level showed a U-shaped relationship with the length of hospital stay. In conclusion, low serum albumin level was an independent predictor of longer hospital stay in patients undergoing PCI for acute coronary syndrome, with shorter stays observed for increasing serum albumin levels. Low serum albumin can be used to identify patients who require longer hospitalization and may need additional nutritional support or interventions to improve their prognosis.

摘要

血清白蛋白水平降低会增加冠心病发病率、死亡率和术后心血管风险。因此,本研究旨在探讨血清白蛋白水平与行经皮冠状动脉介入治疗(PCI)的急性冠状动脉综合征患者住院时间之间的关系。根据血清白蛋白水平,将 350 例患者分为四组。采用单因素和多因素分析来确定与住院时间相关的因素。还对血清白蛋白与住院时间进行了非线性回归分析。多因素分析结果表明,低血清白蛋白水平是住院时间延长的独立预测因子,即使在完全调整的模型中也是如此。在分段线性回归模型中,血清白蛋白水平与住院时间呈 U 型关系。总之,血清白蛋白水平降低是 PCI 治疗急性冠状动脉综合征患者住院时间延长的独立预测因子,随着血清白蛋白水平的升高,住院时间缩短。低血清白蛋白可用于识别需要住院时间较长的患者,并可能需要额外的营养支持或干预措施来改善其预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da17/11470946/101c973a810f/41598_2024_74955_Fig1_HTML.jpg

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