Animal Medicine and Surgery Department, Veterinary Faculty, UCM, Madrid, Spain.
Facultad de Veterinaria, UEX, Cáceres, Spain.
Reprod Domest Anim. 2024 Oct;59 Suppl 3:e14614. doi: 10.1111/rda.14614.
Kenney-Doig scale is considered the international standard method for classifying uterine biopsies in mares; however, its objectivity has been questioned by various studies. In the present study, we analysed the degree of agreement between two pathologists when assessing the same set of 201 uterine biopsies, obtaining a slight to moderate level of agreement (κ = .34/κ = .57). Subsequently, we developed a numerical scale based on the evaluation of histological parameters, including inflammation, fibrosis, glandular density and lymphatic lacunae. Partial scores were summed to obtain a fifth parameter called Summation. The correlation between both scales was demonstrated (p < .0001), and their combined use resulted in a notable increase in the degree of agreement between the two pathologists (κ = .53/κ = .67).
肯尼-道格量表被认为是分类母马子宫活检的国际标准方法；然而，其客观性受到了各种研究的质疑。在本研究中，我们分析了两位病理学家在评估同一组 201 个子宫活检时的一致性程度，得到了轻度到中度的一致性（κ=0.34/κ=0.57）。随后，我们根据组织学参数的评估，包括炎症、纤维化、腺体密度和淋巴腔隙，开发了一个数值量表。部分评分相加得到一个称为总和的第五个参数。两种量表之间的相关性得到了证明（p<0.0001），并且它们的联合使用显著提高了两位病理学家之间的一致性程度（κ=0.53/κ=0.67）。
