A rare case of keratitis due to co-infection with and T5 genotype.

AIMS

This report summarizes clinical findings, diagnosis, management, and long term outcomes of a recalcitrant and keratitis.

METHODS AND MATERIALS

An otherwise healthy male patient presented with a corneal infiltrate with predominantly fungal characteristics, but atypical in terms of progression. The infiltrate remained undiagnosed even after several scrapings, and aqueous tap cultures. Since conventional therapy with antifungals and intrastromal voriconazole injections was ineffective, a therapeutic keratoplasty was done.

RESULTS

The excised corneal button was cultured; molecular identification of the and fungus isolates revealed the rare T5 genotype and the even rarer . Judicious use of antifungals and anti-amoebic drops in the post-operative period, combined with gradual introduction of steroids resulted in favourable visual outcome.

CONCLUSIONS

The T5 is the second most frequent environmental , but rarely isolated clinically. keratitis has been reported only 4 times in the literature. Neither of these have been previously reported from India.