Honda Hiromi, Funahara Madoka, Nose Kanako, Aoki Megumi, Soutome Sakiko, Yanagita Kenichi, Nakamichi Atsuko
School of Oral Health Sciences, Faculty of Dentistry, Kyushu Dental University, Kitakyushu, JPN.
Department of Pediatric Dentistry, Fukuoka Children's Hospital, Fukuoka, JPN.
Cureus. 2024 Sep 12;16(9):e69269. doi: 10.7759/cureus.69269. eCollection 2024 Sep.
Postoperative pneumonia may develop in infants after cardiac surgery; however, only a few reports are available on perioperative oral bacteria in infants. This study aimed to examine preoperative and postoperative salivary bacterial counts in infants undergoing cardiac surgery.
The number of bacteria in the saliva of 105 infants (average age: 20 months) who underwent surgery for congenital heart disease was determined by culturing before and after surgery. Factors associated with changes in the bacterial count were further examined. Patients received systemic antimicrobials for an average of four days immediately before surgery.
Postoperative salivary bacterial counts were higher in older patients, who had erupting teeth and had longer surgical times. The average number of colonies before surgery was 10 CFU/mL; on the day after surgery, this number significantly decreased to 10 CFU/mL. The rate of reduction was especially high in infants without tooth eruption. The total number of bacterial colonies in saliva decreased after surgery, most likely because of the use of systemically administered antibiotics, and the rate of decrease was particularly high in infants without tooth eruptions.
This study examined the preoperative and postoperative salivary bacterial counts in infants undergoing cardiac surgery. In the future, we would like to further examine bacterial flora and the effects of perioperative oral care. This study provides insights into the development of new strategies for preventing and treating surgical site infections and pneumonia in children.
心脏手术后婴儿可能会发生术后肺炎；然而，关于婴儿围手术期口腔细菌的报道却很少。本研究旨在检测接受心脏手术婴儿术前和术后唾液中的细菌数量。
通过对105例（平均年龄：20个月）接受先天性心脏病手术的婴儿术前和术后唾液进行培养，测定细菌数量。进一步研究与细菌数量变化相关的因素。患者在手术前平均接受了4天的全身抗菌药物治疗。
年龄较大、正在出牙且手术时间较长的患者术后唾液细菌数量较高。术前平均菌落数为10 CFU/mL；术后第一天，该数量显著降至10 CFU/mL。未出牙婴儿的细菌数量减少率尤其高。手术后唾液中细菌菌落总数下降，很可能是因为使用了全身抗生素，且未出牙婴儿的下降率特别高。
本研究检测了接受心脏手术婴儿术前和术后唾液中的细菌数量。未来，我们希望进一步研究细菌菌群以及围手术期口腔护理的效果。本研究为制定预防和治疗儿童手术部位感染及肺炎的新策略提供了思路。
