Sone Daichi, Kanemoto Kousuke
Department of Psychiatry, Jikei University School of Medicine, Tokyo, sJapan.
Department of Neuropsychiatry, Aichi Medical University, Nagakute, Japan.
Front Psychiatry. 2024 Sep 27;15:1486667. doi: 10.3389/fpsyt.2024.1486667. eCollection 2024.
Since epilepsy is often complicated by psychiatric symptoms, the contributions of psychiatry are indispensable for the care and improvement of the quality of life of individuals with epilepsy. Moreover, the existence of a bidirectional relationship between epilepsy and psychiatric symptoms was recently proposed, based on the evidence that not only are some psychiatric symptoms more likely than others to follow epilepsy, but also that psychiatric symptoms may precede the onset of epilepsy and the presence of psychiatric symptoms may influence the outcome of treatment for seizures. There has also been a gradual accumulation of neurobiological findings related to psychosis, depressive, and anxiety symptoms that are associated with epilepsy with respect to abnormalities in brain networks and neurotransmission. This mini-review focuses on the neuropsychiatric aspects of epilepsy and proposes that a reconsideration of neuropsychiatry in light of epilepsy findings could serve as a bridge between psychiatry and neurology.
由于癫痫常伴有精神症状，精神病学对于癫痫患者的护理及生活质量改善不可或缺。此外，基于以下证据，近期有人提出癫痫与精神症状之间存在双向关系：不仅某些精神症状比其他症状更易继发于癫痫，而且精神症状可能先于癫痫发作出现，并且精神症状的存在可能影响癫痫治疗的结果。关于与癫痫相关的精神病性、抑郁及焦虑症状，在脑网络和神经传递异常方面的神经生物学研究结果也在逐渐积累。本综述聚焦于癫痫的神经精神方面，并提出根据癫痫研究结果重新审视神经精神病学可成为精神病学与神经病学之间的桥梁。
