Suppr超能文献

吲哚菁绿(ICG)荧光在低收入和中等收入国家(LMIC)一家医院的结直肠手术吻合口边缘血管评估中的应用

Indocyanine Green (ICG) Fluorescence in the Assessment of Vascularity of Anastomotic Margins in Colorectal Surgery in a Lower Middle-Income Country (LMIC) Hospital.

作者信息

Lim Michael Geoffrey L, Lopez Marc Paul J, Onglao Mark Augustine S, Monroy Hermogenes J, Sacdalan Marie Dione P

机构信息

Division of Colorectal Surgery, Department of Surgery, Philippine General Hospital, University of the Philippines Manila.

出版信息

Acta Med Philipp. 2024 Sep 13;58(16):8-13. doi: 10.47895/amp.v58i16.7057. eCollection 2024.

Abstract

BACKGROUND AND OBJECTIVE

One of the uses of indocyanine green (ICG) in the surgical field is the evaluation of the anastomotic margins in colorectal surgery. This is of particular importance because fluorescence imaging may aid in detecting vascular compromise, allowing the surgeon to change the resection margin thereby decreasing the chance of an anastomotic leak. To date, there has been no study with its use locally. This study aimed to determine whether the use of ICG can safely identify if the margins of resection are well-vascularized in patients undergoing left-sided colon or rectal surgery, which in turn may reduce anastomotic leak rates.

METHODS

Through a retrospective study design, the investigators gathered data of patients who underwent left-sided colon or rectal surgery. The groups were divided into those with and without the use of ICG and a comparative data on the anastomotic leak rates were analyzed.

RESULTS

Eighty-six (86) patients with similar patient characteristics, tumor staging, and surgical approach were compared. Both the leak rates identified during the initial hospital stay and at 30 days post-operatively were lower in those where ICG was used (p=0.035, p=0.047, respectively) than those where ICG was not used.

CONCLUSION

ICG fluorescence imaging may reduce the anastomotic leak rates in patients undergoing colorectal surgery.

摘要

背景与目的

吲哚菁绿(ICG)在外科领域的用途之一是评估结直肠手术中的吻合缘。这一点尤为重要,因为荧光成像可能有助于检测血管受损情况,使外科医生能够改变切除边缘,从而降低吻合口漏的几率。迄今为止,尚未有关于其在本地使用的研究。本研究旨在确定ICG的使用能否安全地识别接受左侧结肠或直肠手术患者的切除边缘是否血管化良好,进而可能降低吻合口漏发生率。

方法

通过回顾性研究设计,研究人员收集了接受左侧结肠或直肠手术患者的数据。将这些组分为使用ICG和未使用ICG的两组,并分析吻合口漏发生率的对比数据。

结果

对86例具有相似患者特征、肿瘤分期和手术方式的患者进行了比较。使用ICG的患者在初次住院期间及术后30天的漏发生率均低于未使用ICG的患者(分别为p = 0.035,p = 0.047)。

结论

ICG荧光成像可能降低结直肠手术患者的吻合口漏发生率。

相似文献

3
Near-infrared fluorescence angiography for colorectal surgery is associated with a reduction of anastomotic leak rate.
Updates Surg. 2020 Dec;72(4):991-998. doi: 10.1007/s13304-020-00758-x. Epub 2020 Apr 6.
4
Cost analysis of indocyanine green fluorescence angiography for prevention of anastomotic leakage in colorectal surgery.
Surg Endosc. 2022 Dec;36(12):9281-9287. doi: 10.1007/s00464-022-09166-1. Epub 2022 Mar 15.
5
Indocyanine green-enhanced fluorescence to assess bowel perfusion during laparoscopic colorectal resection.
Surg Endosc. 2016 Jul;30(7):2736-42. doi: 10.1007/s00464-015-4540-z. Epub 2015 Oct 20.
8
Indocyanine green fluorescence angiography to evaluate anastomotic perfusion in colorectal surgery.
Int J Colorectal Dis. 2020 Jun;35(6):1133-1139. doi: 10.1007/s00384-020-03592-0. Epub 2020 Apr 14.

本文引用的文献

4
Indocyanine Green-Enhanced Colorectal Surgery-between Being Superfluous and Being a Game-Changer.
Diagnostics (Basel). 2020 Sep 24;10(10):742. doi: 10.3390/diagnostics10100742.
7
Quantitative analysis of colon perfusion pattern using indocyanine green (ICG) angiography in laparoscopic colorectal surgery.
Surg Endosc. 2019 May;33(5):1640-1649. doi: 10.1007/s00464-018-6439-y. Epub 2018 Sep 10.
9
Perfusion assessment in laparoscopic left-sided/anterior resection (PILLAR II): a multi-institutional study.
J Am Coll Surg. 2015 Jan;220(1):82-92.e1. doi: 10.1016/j.jamcollsurg.2014.09.015. Epub 2014 Sep 28.
10
Risk factors for anastomotic leakage after anterior resection for rectal cancer.
JAMA Surg. 2013 Jan;148(1):65-71. doi: 10.1001/2013.jamasurg.2.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验