Lim Michael Geoffrey L, Lopez Marc Paul J, Onglao Mark Augustine S, Monroy Hermogenes J, Sacdalan Marie Dione P
Division of Colorectal Surgery, Department of Surgery, Philippine General Hospital, University of the Philippines Manila.
Acta Med Philipp. 2024 Sep 13;58(16):8-13. doi: 10.47895/amp.v58i16.7057. eCollection 2024.
One of the uses of indocyanine green (ICG) in the surgical field is the evaluation of the anastomotic margins in colorectal surgery. This is of particular importance because fluorescence imaging may aid in detecting vascular compromise, allowing the surgeon to change the resection margin thereby decreasing the chance of an anastomotic leak. To date, there has been no study with its use locally. This study aimed to determine whether the use of ICG can safely identify if the margins of resection are well-vascularized in patients undergoing left-sided colon or rectal surgery, which in turn may reduce anastomotic leak rates.
Through a retrospective study design, the investigators gathered data of patients who underwent left-sided colon or rectal surgery. The groups were divided into those with and without the use of ICG and a comparative data on the anastomotic leak rates were analyzed.
Eighty-six (86) patients with similar patient characteristics, tumor staging, and surgical approach were compared. Both the leak rates identified during the initial hospital stay and at 30 days post-operatively were lower in those where ICG was used (p=0.035, p=0.047, respectively) than those where ICG was not used.
ICG fluorescence imaging may reduce the anastomotic leak rates in patients undergoing colorectal surgery.
吲哚菁绿(ICG)在外科领域的用途之一是评估结直肠手术中的吻合缘。这一点尤为重要,因为荧光成像可能有助于检测血管受损情况,使外科医生能够改变切除边缘,从而降低吻合口漏的几率。迄今为止,尚未有关于其在本地使用的研究。本研究旨在确定ICG的使用能否安全地识别接受左侧结肠或直肠手术患者的切除边缘是否血管化良好,进而可能降低吻合口漏发生率。
通过回顾性研究设计,研究人员收集了接受左侧结肠或直肠手术患者的数据。将这些组分为使用ICG和未使用ICG的两组,并分析吻合口漏发生率的对比数据。
对86例具有相似患者特征、肿瘤分期和手术方式的患者进行了比较。使用ICG的患者在初次住院期间及术后30天的漏发生率均低于未使用ICG的患者(分别为p = 0.035,p = 0.047)。
ICG荧光成像可能降低结直肠手术患者的吻合口漏发生率。