吲哚菁绿近红外荧光成像检测结直肠癌转移性淋巴结的敏感性和特异性：系统评价与Meta分析
Sensitivity and specificity of indocyanine green near-infrared fluorescence imaging in detection of metastatic lymph nodes in colorectal cancer: Systematic review and meta-analysis.
作者信息
Emile Sameh H, Elfeki Hossam, Shalaby Mostafa, Sakr Ahmad, Sileri Pierpaolo, Laurberg Søren, Wexner Steven D
机构信息
Mansoura Faculty of Medicine, Department of General Surgery, Colorectal Surgery Unit, Mansoura University, Mansoura, Dakahlia, Egypt.
Department of Surgery, Aarhus University Hospital, Aarhus, Denmark.
出版信息
J Surg Oncol. 2017 Nov;116(6):730-740. doi: 10.1002/jso.24701. Epub 2017 Jun 1.
This review aimed to determine the overall sensitivity and specificity of indocyanine green (ICG) near-infrared (NIR) fluorescence in sentinel lymph node (SLN) detection in Colorectal cancer (CRC). A systematic search in electronic databases was conducted. Twelve studies including 248 patients were reviewed. The median sensitivity, specificity, and accuracy rates were 73.7, 100, and 75.7. The pooled sensitivity and specificity rates were 71% and 84.6%. In conclusion, ICG-NIR fluorescence is a promising technique for detecting SLNs in CRC.
本综述旨在确定吲哚菁绿（ICG）近红外（NIR）荧光在结直肠癌（CRC）前哨淋巴结（SLN）检测中的总体敏感性和特异性。我们在电子数据库中进行了系统检索。对12项研究（包括248例患者）进行了综述。中位敏感性、特异性和准确率分别为73.7、100和75.7。合并的敏感性和特异性率分别为71%和84.6%。总之，ICG-NIR荧光是一种用于检测CRC中SLN的有前景的技术。
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