一只兔子疑似骨外骨肉瘤的组织病理学和免疫组织化学分析（）。
Histopathological and immunohistochemical analysis of a suspected extraskeletal osteosarcoma in a rabbit ().
作者信息
de Andrade Julia Penna, Soares Camilla Faria, Junqueira André Luiz de Moura, Santos Daniel Reis, de Carvalho Marcelo Pires Nogueira, Nakagaki Karen Yumi Ribeiro, Viscone Érica Almeida, Borges Lize, Cassali Geovanni Dantas, Horta Rodrigo Dos Santos
机构信息
Veterinarian, Resident. Programa de Residência em Saúde Única com Ênfase em Interface Saúde Humana e Silvestre- Escola de Veterinária da Universidade Federal de Minas Gerais (UFMG). Pampulha, Belo Horizonte, MG, Brazil.
Undergraduate in Veterinary Medicine, UFMG. Pampulha, Belo Horizonte, MG, Brazil.
出版信息
Braz J Vet Med. 2024 Oct 7;46:e003324. doi: 10.29374/2527-2179.bjvm003324. eCollection 2024.
An 8-year-old male rabbit () presented with a subcutaneous mass in the proximal region of the fourth and accessory digit measuring 5.5 x 3.5 x 5.2cm. The mass was non-alopecic and exhibited irregular surface, ulceration and necrosis with predominantly pale and light brown coloring. Radiography revealed no involvement of bone and adjacent periosteum. The mass was marginally resected and the electrochemotherapy (ECT) was performed on the surgical bed. Histopathology and immunohistochemical analysis revealed positive reactions for Vimentin, Runx-2 and ki-67, leading to a diagnosis of extraskeletal osteosarcoma (ESOS). This report described a case of ESOS in a rabbit, thereby delineating its clinical presentation, anatomopathological characteristics, diagnostic modalities and recommended therapeutic interventions.
一只8岁雄性兔子（）在第四指及副指近端区域出现一个皮下肿块，大小为5.5×3.5×5.2厘米。该肿块无脱毛现象，表面不规则，有溃疡和坏死，主要颜色为淡色和浅棕色。放射检查显示骨骼及相邻骨膜未受累。对肿块进行了边缘切除，并在手术床上进行了电化学疗法（ECT）。组织病理学和免疫组织化学分析显示波形蛋白、Runx-2和ki-67呈阳性反应，诊断为骨外骨肉瘤（ESOS）。本报告描述了一例兔子的ESOS病例，从而阐述了其临床表现、解剖病理学特征、诊断方法及推荐的治疗干预措施。
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