Clair-Sullivan Natalie St, Vera Jaime H, Maddocks Matthew, Harding Richard, Levett Thomas, Roberts Jonathan, Adler Zoe, Bremner Stephen, Pargeter Gary, Bristowe Katherine
King's College London, Cicely Saunders Institute of Palliative Care, Policy & Rehabilitation, London, UK.
Department of Global Health and Infection, Brighton and Sussex Medical School, Brighton, UK.
HIV Med. 2025 Mar;26(3):339-349. doi: 10.1111/hiv.13722. Epub 2024 Oct 13.
Advances in antiretroviral therapy have meant that the focus of HIV care has shifted to chronic disease management. The HIV population is ageing, and the prevalence of frailty is increasing. This study aimed to explore the perspectives and experiences of the impact of living with HIV and frailty and priority outcomes in relation to wellbeing and ageing.
In-depth qualitative interviews were undertaken with older people living with HIV who screened positive for frailty using the FRAIL scale. Participants were recruited from a UK outpatient HIV clinic. Interviews were analysed using reflexive thematic analysis.
In total, 24 people living with HIV were interviewed. Frailty was described as not being able to do the things you could and living with limitations that impacted physical, psychological and social wellbeing. Being identified as frail was not always surprising, but acceptance of this diagnosis required an understanding of what frailty means and what they can do to address it. For people living with HIV, the word 'frail' was largely acceptable when its clinical meaning was explained. However, participants questioned whether a different term is needed if this is a new 'HIV-associated frailty'. Priority outcomes were slowing the progression of frailty, retaining independence and being treated holistically.
When talking about frailty with people living with HIV, professionals need to balance honesty and sensitivity and provide clear information about the meaning and impact for the person. Holistic management plans must recognize the physical and psycho-social impact of frailty and prioritize slowing its progression and reducing its impact on independence.
抗逆转录病毒疗法的进展意味着艾滋病毒护理的重点已转向慢性病管理。艾滋病毒感染者群体正在老龄化，虚弱的患病率也在上升。本研究旨在探讨感染艾滋病毒和身体虚弱对生活的影响的观点和经历，以及与幸福感和老龄化相关的优先结果。
对使用FRAIL量表筛查出身体虚弱呈阳性的老年艾滋病毒感染者进行了深入的定性访谈。参与者从英国一家门诊艾滋病毒诊所招募。访谈采用反思性主题分析进行分析。
总共采访了24名艾滋病毒感染者。身体虚弱被描述为无法做自己能做的事情，并且生活受到限制，这影响了身体、心理和社会幸福感。被认定为身体虚弱并不总是令人惊讶的，但接受这一诊断需要了解身体虚弱的含义以及他们可以采取什么措施来应对。对于艾滋病毒感染者来说，当解释了“身体虚弱”一词的临床含义时，这个词在很大程度上是可以接受的。然而，参与者质疑，如果这是一种新的“与艾滋病毒相关的身体虚弱”，是否需要一个不同的术语。优先结果是减缓身体虚弱的进展、保持独立以及接受整体治疗。
在与艾滋病毒感染者谈论身体虚弱时，专业人员需要在诚实和敏感之间取得平衡，并提供关于其含义和对个人影响的明确信息。整体管理计划必须认识到身体虚弱对身体和心理社会的影响，并将减缓其进展和减少其对独立性的影响作为优先事项。
