, Winston-Salem, NC, USA.
Med Oncol. 2024 Oct 14;41(11):272. doi: 10.1007/s12032-024-02500-8.
Successful personalized oncology today depends on clinicians taking advantage of the extensive, evidence-based information provided by the National Comprehensive Cancer Network (NCCN) Guidelines, which arguably represent the most important advance in cancer care occurring in the last many decades. Personalized oncology also demands that clinicians present guideline information to each patient in a thorough, comprehendible and unbiased manner. Finally, the patient's ability to process that information for shared decision-making about whether an intervention is consistent with their personal preferences, goals and values is perhaps the most important ingredient in truly personalized oncology care. Here, the ethics of sometimes transgressing from the NCCN guidelines with the aim of more personalized care is discussed.
如今，成功的肿瘤个体化治疗依赖于临床医生充分利用美国国家综合癌症网络（NCCN）指南提供的广泛而基于证据的信息，这可以说是过去几十年中癌症治疗最重要的进展。肿瘤个体化治疗还要求临床医生以全面、可理解和无偏见的方式向每位患者提供指南信息。最后，患者是否有能力处理这些信息，以便就干预措施是否符合其个人偏好、目标和价值观做出共同决策，这也许是真正的肿瘤个体化治疗中最重要的因素。在这里，我们讨论了有时超越 NCCN 指南以达到更个体化治疗的伦理问题。
