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评估内路房角成形术联合白内障手术治疗青光眼患者的 1 年疗效和安全性。

Evaluating the 1-year success and safety of ab interno canaloplasty in combination with cataract surgery in glaucoma patients.

机构信息

Department of Ophthalmology, University Hospital RWTH Aachen, Pauwelsstraße 30, 52074, Aachen, Germany.

Augenzentrum Am Annapark Alsdorf, Steigerweg 3, 52477, Aachen, Germany.

出版信息

Int Ophthalmol. 2024 Oct 14;44(1):406. doi: 10.1007/s10792-024-03325-0.

Abstract

PURPOSE

To evaluate the treatment success and safety of ab interno canaloplasty (AbiC) combined with cataract surgery in glaucoma patients.

METHODS

The prospective case study included 43 eyes that received an AbiC combined with cataract surgery (age 73.3 ± 8.2 years). The 360° microcatheterization and viscodilatation of the Schlemm's canal was conducted using VISCO 360 (Sight Sciences, CA, USA). The observation period was 12 months with visits at 2 and 6 as well as 12 months, 7 eyes were lost to follow up.

RESULTS

The preoperative IOP was 19.8 ± 4.9 mmHg and was reduced to 14.5 ± 2.8 mmHg 12 months after AbiC (p < 0.0001). The relative IOP reduction was 23.6 ± 23.1% after 12 months. Topical glaucoma medication was also reduced from 2.4 ± 1.1 drugs to 1.1 ± 1.4 (p < 0.001) after 12 months. The complete surgical success rate (defined as IOP < 18 mmHg without topical therapy) was 31.6% whereas the qualified surgical success was 89.5% (IOP < 18 mmHg, with local therapy) There were no relevant intra- or postoperative complications.

CONCLUSION

AbiC in combination with cataract surgery is a safe and effective procedure to achieve a significant reduction of IOP and local glaucoma medication 12 months after surgery.

摘要

目的

评估内路房水引流管成形术(AbiC)联合白内障手术治疗青光眼患者的疗效和安全性。

方法

前瞻性病例研究纳入 43 例(年龄 73.3±8.2 岁)接受 AbiC 联合白内障手术的患者。使用 VISCO 360(Sight Sciences,CA,美国)对施累姆氏管进行 360°微导管化和黏弹性扩张。观察期为 12 个月,分别在术后 2、6 个月以及 12 个月进行随访,其中 7 只眼失访。

结果

术前眼压为 19.8±4.9mmHg,AbiC 术后 12 个月降低至 14.5±2.8mmHg(p<0.0001)。术后 12 个月相对眼压降低 23.6±23.1%。术后 12 个月,局部降眼压药物也从 2.4±1.1 种减少至 1.1±1.4 种(p<0.001)。完全手术成功率(定义为眼压<18mmHg,无需局部治疗)为 31.6%,合格手术成功率为 89.5%(眼压<18mmHg,局部治疗)。无相关的术中或术后并发症。

结论

AbiC 联合白内障手术是一种安全有效的方法,可在术后 12 个月显著降低眼压和局部降眼压药物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e9a8/11473546/8e455c0767e5/10792_2024_3325_Fig1_HTML.jpg

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