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急性呼吸衰竭接受机械通气患者的程序化镇静护理与传统护理的比较。

Comparison of programmed sedation care with conventional care in patients receiving mechanical ventilation for acute respiratory failure.

作者信息

Wang Jiantang, Li Yuntao, Han Yujuan, Yuan Xinyu

机构信息

Pulmonary and Critical Care Medicine, The Fourth Affiliated Hospital of Soochow University, Suzhou, 215000, China.

Department of Emergency Medicine, The First Affiliated Hospital of Soochow University, Suzhou, 215000, China.

出版信息

Ir J Med Sci. 2025 Feb;194(1):289-296. doi: 10.1007/s11845-024-03825-z. Epub 2024 Oct 14.

Abstract

OBJECTIVE

The aim of this study is to evaluate the effectiveness of planned sedation therapy in comparison to standard care for patients receiving mechanical ventilation for acute respiratory failure (ARF).

METHOD

The research included a total of sixty individuals who underwent mechanical ventilation for acute respiratory failure (ARF). Utilizing the random number table method, these patients were randomized at random to either the planned sedation care group (Group PSC) or the conventional care group (Group C). The objective was to assess and contrast the impact of treatment on the two groups. Significantly shorter durations of mechanical ventilation, sedative use, ICU therapy, length of stay, incidence of delirium, and adverse events were observed in Group PSC compared with Group C (P < 0.05). A higher 1-month survival rate following mechanical ventilation, a higher post-intervention forced expiratory volume in one second (FEV1) as a percentage of the expected value, a higher post-intervention forced vital capacity (FVC), and a higher patient family care satisfaction rate were observed in Group PSC compared to Group C (P < 0.05).

CONCLUSION

The scheduled administration of sedative therapy in patients receiving mechanical ventilation for acute respiratory failure (ARF) offers significant, reliable, and effective therapeutic benefits.

摘要

目的

本研究旨在评估计划镇静治疗与标准护理相比,对急性呼吸衰竭(ARF)接受机械通气患者的有效性。

方法

该研究共纳入60例因急性呼吸衰竭接受机械通气的患者。采用随机数字表法,将这些患者随机分为计划镇静护理组(PSC组)和常规护理组(C组)。目的是评估和对比治疗对两组的影响。与C组相比,PSC组机械通气时间、镇静药物使用时间、重症监护病房(ICU)治疗时间、住院时间、谵妄发生率及不良事件明显缩短(P<0.05)。与C组相比,PSC组机械通气后1个月生存率更高,干预后一秒用力呼气量(FEV1)占预期值的百分比更高,干预后用力肺活量(FVC)更高,患者家属护理满意度更高(P<0.05)。

结论

对急性呼吸衰竭(ARF)接受机械通气的患者进行计划性镇静治疗具有显著、可靠且有效的治疗益处。

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