Enayati Zakaria, Cacace Anthony T
Department of Communication Sciences & Disorders, Wayne State University, Detroit, MI.
Am J Audiol. 2024 Dec 2;33(4):1092-1103. doi: 10.1044/2024_AJA-24-00075. Epub 2024 Oct 14.
The purpose of this study is to describe the effects of diabetes mellitus (DM) on vestibular and balance system functions in humans. Because Type 2 diabetes (T2D) represents the majority of individuals affected by this condition, this subgroup is the main focus of this tutorial.
Evidence of dysfunction is based on epidemiological, anatomical, physiological, neuroimaging, and clinical findings. Preventative measures, therapeutic interventions, and other mitigating factors are also given consideration.
Experimental and clinical findings support the notion that T2D damages vestibular and balance systems to the extent that these effects are more prevalent in patients with higher blood glucose levels and longer duration of the disease. Evidence indicates that T2D increases the occurrence and re-occurrence rates of benign paroxysmal positional vertigo, particularly when it occurs in conjunction with hypertension, osteoarthritis, and otologic disorders like Ménière's disease. Type 2 diabetes also impairs vestibular compensation, which is exacerbated by disease duration. Investigational and clinical studies suggest that galvanic stimulation of the vestibular system can be effective in reducing blood glucose levels and improving rehabilitation outcomes.
Because DM is a chronic metabolic condition affecting cochlear, vestibular, and balance system functions, lowering blood glucose levels through diet, pharmacological interventions, and exercise can be effective in mitigating dysfunction.
本研究的目的是描述糖尿病(DM)对人体前庭和平衡系统功能的影响。由于2型糖尿病(T2D)患者占受该疾病影响个体的大多数,因此该亚组是本教程的主要关注点。
功能障碍的证据基于流行病学、解剖学、生理学、神经影像学和临床研究结果。同时也考虑了预防措施、治疗干预和其他缓解因素。
实验和临床研究结果支持以下观点,即T2D会损害前庭和平衡系统,且在血糖水平较高和病程较长的患者中这些影响更为普遍。有证据表明,T2D会增加良性阵发性位置性眩晕的发生和复发率,尤其是当它与高血压、骨关节炎以及梅尼埃病等耳科疾病同时发生时。2型糖尿病还会损害前庭代偿,且病程会加剧这种损害。研究和临床研究表明,前庭系统的电刺激可有效降低血糖水平并改善康复效果。
由于DM是一种影响耳蜗、前庭和平衡系统功能的慢性代谢性疾病,通过饮食、药物干预和运动降低血糖水平可有效减轻功能障碍。