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[电热针辅助治疗稳定期慢性阻塞性肺疾病:一项随机对照试验]

[Stable chronic obstructive pulmonary disease treated by adjunctive therapy of electrothermal acupuncture: a randomized controlled trial].

作者信息

Li Shan, Xia Yuqing, Wang Haijian, Lai Xue, Wu Wei

机构信息

Department of Respiration, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China.

Clinic of Electrothermal Acupuncture, Wangjing Hospital of China Academy of Chinese Medical Sciences, Beijing 100102, China.

出版信息

Zhongguo Zhen Jiu. 2024 Oct 12;44(10):1125-9. doi: 10.13703/j.0255-2930.20231220-k0002.

DOI:10.13703/j.0255-2930.20231220-k0002
PMID:39401809
Abstract

OBJECTIVE

To assess the effect and safety of electrothermal acupuncture in adjunctive treatment of stable chronic obstructive pulmonary disease (COPD) in patients.

METHODS

Sixty-six stable COPD patients were randomly divided into an observation group and a control group, with 33 cases in each group. The patients in the control group were treated with bronchodilator inhalation combined with respiratory training for 4 weeks. In the observation group, on the basis of the treatment as the control group, electrothermal acupuncture was delivered at bilateral Quchi (LI 11), Zusanli (ST 36) and Sanyinjiao (SP 6), and the conventional filiform needling was operated at the supplementary acupoints selected according to the individual syndrome. The interventions in the observation group were given once every two days, 3 treatments a week, for consecutive 4 weeks. Before and after treatment completion, the lung functions (forced expiratory volume in the first second [FEV1], forced vital capacity [FVC], FEV1/FVC and the percentage of diffusing capacity of the lungs for carbon monoxide [DLCO%]), 6 min walking distance (6MWD) and the score of COPD assessment test (CAT) were compared between the two groups. The attacks of acute exacerbation were recorded in 1-year follow-up visit in the two groups and the safety of electrothermal acupuncture was evaluated.

RESULTS

After treatment, FEV1, FVC, FEV1/FVC, DLCO% and 6MWD were increased (<0.01, <0.05), and CAT scores were decreased (<0.01) in the two groups compared with those before treatment. FEV1, FVC, FEV1/FVC and 6MWD were higher and CAT score was lower in the observation group when compared with those of the control group (<0.05). In the 1-year follow-up visit, the cases of acute exacerbation in the observation group were fewer than that in the control group (<0.05). There were no treatment-related adverse reactions in the observation group.

CONCLUSION

On the basis of bronchodilator inhalation and respiratory training, electrothermal acupuncture can ameliorate the lung function, strengthen motor ability, reduce the cases of acute exacerbation safely and effectively in the patients with stable COPD.

摘要

目的

评估电热针辅助治疗稳定期慢性阻塞性肺疾病(COPD)患者的疗效及安全性。

方法

将66例稳定期COPD患者随机分为观察组和对照组,每组33例。对照组患者采用吸入支气管扩张剂联合呼吸训练治疗4周。观察组在对照组治疗的基础上,于双侧曲池(LI 11)、足三里(ST 36)和三阴交(SP 6)进行电热针治疗,并根据个体证候选取辅助穴位进行常规毫针针刺。观察组每两天进行1次干预,每周治疗3次,连续治疗4周。治疗结束前后,比较两组患者的肺功能(第1秒用力呼气容积[FEV1]、用力肺活量[FVC]、FEV1/FVC和一氧化碳弥散量百分比[DLCO%])、6分钟步行距离(6MWD)及慢性阻塞性肺疾病评估测试(CAT)评分。记录两组患者1年随访期间急性加重发作情况,并评估电热针针针针的安全性。

结果

治疗后,两组患者的FEV1、FVC、FEV1/FVC、DLCO%及6MWD均升高(<0.01,<0.05),CAT评分降低(<0.01)。与对照组相比,观察组的FEV1、FVC、FEV1/FVC及6MWD更高,CAT评分更低(<0.05)。1年随访期间,观察组急性加重发作例数少于对照组(<0.05)。观察组未出现与治疗相关的不良反应。

结论

在吸入支气管扩张剂和呼吸训练的基础上,电热针可安全有效地改善稳定期COPD患者的肺功能,增强运动能力,减少急性加重发作次数。

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