Tong Juan, Guo Yong-mei, He Ying, Li Gui-yuan, Chen Fang, Yao Hong
Zhongguo Zhen Jiu. 2014 Sep;34(9):846-50.
To verify the regulatory effects of acupuncture on exercise tolerance in patients with chronic obstructive pulmonary disease (COPD) at stable phase.
Thirty cases of COPD were randomly divided into a treatment group (16 cases) and a placebo group (14 cases). Based on specified aerobic exercise, acupuncture was applied in the treatment group and placebo acupuncture was used in the placebo group. The acupoints included Danzhong (CV 17), Rugen (ST 18), Guanyuan (CV 4), Zhongwan (CV 12), Tianshu (ST 25) and so on. The needle did not penetrate into the skin for the placebo group. The treatment was required for 2 to 3 times per week for totally 5 weeks. The indices of exercise tolerance, including 6-min walking distance (6-MWD), exercise time, maximum oxygen uptake (VO2max) forced expiratory volume in 1 second (FEV1)/forced vital capacity (FVC), maximum ventilatory volume (MVV), St. George respiratory questionnaire (SGRQ) were observed in two groups before and after treatment.
(1) Exercise tolerance: the differences of 6-MWD and exercise time were statistically significant between groups, which were more superior in the treatment group (both P<0.01); the VO2max was significantly increased after treatment in the treatment group (P<0.05), but there was no difference between two groups (P>0.05). (2) Pulmonary ventilation function: the differences of FEV1%, FEV1/FVC and MVV% were statistically significant between groups, which were more superior in the treatment group (P<0.05, P<0.01); (3) SGRQ: the SGRQ was significantly improved after treatment in the treatment group (P<0.05), but there was no difference between two groups (P>0.05).
The acupuncture could improve the exercise tolerance in patients with chronic obstructive pulmonary disease at stable phase, and shorten the onset time of aerobic exercise. Besides, acupuncture combined with aerobic exercise could effectively improve the pulmonary function.
验证针刺对稳定期慢性阻塞性肺疾病（COPD）患者运动耐力的调节作用。
将30例COPD患者随机分为治疗组（16例）和安慰剂组（14例）。在规定有氧运动基础上，治疗组采用针刺治疗，安慰剂组采用假针刺治疗。穴位包括膻中（CV 17）、乳根（ST 18）、关元（CV 4）、中脘（CV 12）、天枢（ST 25）等。安慰剂组针刺不刺入皮肤。每周治疗2至3次，共5周。观察两组治疗前后运动耐力指标，包括6分钟步行距离（6-MWD）、运动时间、最大摄氧量（VO2max）、第1秒用力呼气容积（FEV1）/用力肺活量（FVC）、最大通气量（MVV）、圣乔治呼吸问卷（SGRQ）。
（1）运动耐力：两组间6-MWD和运动时间差异有统计学意义，治疗组更优（均P<0.01）；治疗组治疗后VO2max显著升高（P<0.05），但两组间无差异（P>0.05）。（2）肺通气功能：两组间FEV1%、FEV1/FVC和MVV%差异有统计学意义，治疗组更优（P<0.05，P<0.01）；（3）SGRQ：治疗组治疗后SGRQ显著改善（P<0.05），但两组间无差异（P>0.05）。
针刺可提高稳定期慢性阻塞性肺疾病患者的运动耐力，缩短有氧运动起效时间。此外，针刺联合有氧运动可有效改善肺功能。
