Department of Anesthesiology and Reanimation, Health Science University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.
Department of Anesthesiology and Reanimation, Silvan State Hospital, Diyarbakır, Turkey.
BMC Anesthesiol. 2024 Oct 14;24(1):369. doi: 10.1186/s12871-024-02748-7.
Pediatric central nervous system tumors are the most common solid tumors in children and leading cause of cancer-related morbidity and mortality. Various factors may influence the practice of blood transfusion during this tumor diagnosis. The primary aim of this study was to determine the factors that may influence intraoperative blood transfusion in pediatric patients undergoing surgery for intracranial tumors and to predict patients who may require blood transfusion.
A retrospective study was performed in all pediatric patients younger than 15 years who underwent craniotomy for brain tumor removal from January 2018 to December 2023 in our institution. Preoperative, intraoperative and postoperative data were collected from medical and store anesthesia records. The predictors of intraoperative blood transfusion were determined using multivariate logistic regression.
A total of 138 patients were enrolled in the study, of whom 62 (44.9%) required intraoperative blood transfusion. In multivariate regression analysis age < 4 years and operating time > 490 min were determined as independent variables in terms of need for intraoperative blood transfusion. It was determined that the need for transfusion was higher in patient who were operated on urgently and patients with comorbidities (p = 0.023, p = 0.005).
In conclusion, the findings obtained in this study suggest that age and surgical duration are independent risk factors for intraoperative blood transfusion in pediatric patients undergoing surgery for intracranial tumors. Particularly, in younger patients and prolonged surgeries, closer monitoring and awareness may enhance early detection, leading to the prevention of complications.
小儿中枢神经系统肿瘤是儿童中最常见的实体肿瘤，也是癌症相关发病率和死亡率的主要原因。在诊断这类肿瘤的过程中，各种因素可能会影响输血的实施。本研究的主要目的是确定影响颅内肿瘤手术患儿术中输血的因素，并预测可能需要输血的患者。
本研究对 2018 年 1 月至 2023 年 12 月期间在我院接受开颅手术切除脑肿瘤的所有 15 岁以下小儿患者进行了回顾性研究。从医疗和麻醉记录中收集了术前、术中及术后数据。使用多变量逻辑回归确定术中输血的预测因素。
本研究共纳入 138 例患者，其中 62 例（44.9%）需要术中输血。多变量回归分析显示，年龄<4 岁和手术时间>490 分钟是术中需要输血的独立变量。研究发现，紧急手术和合并症患者的输血需求更高（p=0.023，p=0.005）。
总之，本研究结果表明，年龄和手术时间是小儿颅内肿瘤手术患者术中输血的独立危险因素。特别是在年龄较小和手术时间较长的患者中，更密切的监测和意识可能有助于早期发现，从而预防并发症。
