Ranjbaran Mohammad Erfan, Kazemi Maryam
Noncommunicable Disease Research Center, Fasa University of Medical Sciences, Fasa, Iran.
BMC Rheumatol. 2024 Oct 15;8(1):53. doi: 10.1186/s41927-024-00429-z.
The prevalence of Rheumatoid Arthritis (RA) has been steadily increasing over the last thirty years, particularly among women. Due to the conflicting results of various studies on the link between rheumatoid arthritis and reproductive health, we have undertaken this study to explore their relationship.
This cross-sectional study utilized primary data from5557 women involved in the Fasa Persian Cohort in the years 2013 to 2018. The study examined the frequency of RA and its association with various factors related to reproductive health, including age at first pregnancy, number of alive children, history of abortion, and infertility. SPSS software was utilized for data analysis, with the significance level set at p < 0.05.
5557 women with an average age of 48.6 ± 9.5 years participated. Of these women, 7.2% were diagnosed with rheumatoid disease, with an average onset age of 38.2 ± 15.2. The study did not find a significant correlation between RA and factors such as number of pregnancies, age at first pregnancy, duration of breastfeeding and number of children.
The study suggests that the experience of RA is independent of gynecological, obstetric factors, or reproductive life. This finding may provide reassurance to women affected by RA.
在过去三十年中，类风湿关节炎（RA）的患病率一直在稳步上升，尤其是在女性中。由于关于类风湿关节炎与生殖健康之间联系的各种研究结果相互矛盾，我们开展了这项研究以探讨它们之间的关系。
这项横断面研究利用了2013年至2018年参与法萨波斯队列研究的5557名女性的原始数据。该研究调查了类风湿关节炎的发病率及其与生殖健康相关的各种因素的关联，包括初孕年龄、存活子女数、流产史和不孕情况。使用SPSS软件进行数据分析，显著性水平设定为p < 0.05。
5557名平均年龄为48.6±9.5岁的女性参与了研究。在这些女性中，7.2%被诊断患有类风湿疾病，平均发病年龄为38.2±15.2岁。该研究未发现类风湿关节炎与怀孕次数、初孕年龄、母乳喂养时间和子女数量等因素之间存在显著相关性。
该研究表明，类风湿关节炎的患病情况独立于妇科、产科因素或生殖生活。这一发现可能会让受类风湿关节炎影响的女性感到安心。
