术前口服碳水化合物对日间口腔手术患者术后恢复质量的影响：一项随机对照试验。
Effect of preoperative oral carbohydrate on the postoperative recovery quality of patients undergoing daytime oral surgery: a randomized controlled trial.
作者信息
Tang Weixiang, Meng Gaige, Yang Chen, Sun Yue, Zhong Weiwei, Lu Yao
机构信息
Department of Anesthesiology, Ambulatory Surgery Center, The First Affiliated Hospital of Anhui Medical University, Hefei, 230022, China.
出版信息
Perioper Med (Lond). 2024 Oct 14;13(1):102. doi: 10.1186/s13741-024-00459-8.
BACKGROUND
Preoperative oral carbohydrate intake can improve the postoperative recovery of fasting patients in many kinds of surgeries; however, the effect of carbohydrates on patients undergoing daytime oral surgery is still unclear. This study was designed to evaluate the effect of preoperative oral carbohydrate intake on the quality of recovery of patients undergoing daytime oral surgery using the quality of recovery-15 (QoR-15) questionnaire.
METHODS
Ninety-two patients scheduled for daytime oral surgery were randomly allocated to the midnight fasting group (F group, n = 45) or the carbohydrate-Outfast loading group (O group, n = 47). Participants in the F group fasted from midnight the day before surgery. Patients in the O group also fasted but received the Outfast drink (4 ml/kg) 2-3 h before the induction of anesthesia. QoR-15 questionnaire, patient well-being, and satisfaction were assessed before anesthesia induction and 24 h after surgery. Perioperative blood glucose, postoperative exhaust time, and adverse events were also recorded.
RESULTS
The QoR-15 scores were significantly higher in the O group than in the F group preoperatively and postoperatively. Seven parameters representing patient well-being evaluated on a numeric rating scale (NRS, 0-10) were lower in the O group than in the F group postoperatively, except for the hunger and sleep quality scores. Patient satisfaction scores on a 5-point scale were higher in the O group than in the F group preoperatively and postoperatively. Meanwhile, the postoperative exhaust time was significantly shorter in the O group compared to the F group, while there were no significant differences in blood glucose concentrations between two groups.
CONCLUSIONS
Preoperative oral carbohydrate intake could improve postoperative recovery quality, well-being, and satisfaction of patients undergoing daytime oral surgery 24 h after surgery, and may serve as a treatment option for patients undergoing daytime oral surgery.
TRIAL REGISTRATION
This trial was registered in the Chinese Clinical Trial Registry (ChiCTR2100053753) on 28/11/2021.
背景
术前口服碳水化合物可改善多种手术中禁食患者的术后恢复情况；然而，碳水化合物对日间口腔手术患者的影响仍不明确。本研究旨在使用恢复质量-15（QoR-15）问卷评估术前口服碳水化合物对日间口腔手术患者恢复质量的影响。
方法
92例计划进行日间口腔手术的患者被随机分为午夜禁食组（F组，n = 45）或碳水化合物预负荷组（O组，n = 47）。F组患者从手术前一天午夜开始禁食。O组患者同样禁食，但在麻醉诱导前2 - 3小时饮用预负荷饮料（4毫升/千克）。在麻醉诱导前和术后24小时评估QoR-15问卷、患者的舒适度和满意度。还记录围手术期血糖、术后排气时间和不良事件。
结果
术前和术后O组的QoR-15评分均显著高于F组。除饥饿和睡眠质量评分外，术后用数字评分量表（NRS，0 - 10）评估的代表患者舒适度的七个参数，O组低于F组。术前和术后，O组患者5分制满意度评分均高于F组。同时，O组术后排气时间明显短于F组，而两组血糖浓度无显著差异。
结论
术前口服碳水化合物可改善日间口腔手术患者术后24小时的恢复质量、舒适度和满意度，可作为日间口腔手术患者的一种治疗选择。
试验注册
本试验于2021年11月28日在中国临床试验注册中心（ChiCTR2100053753）注册。
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