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脊髓损伤合并颈椎骨折患者术后深静脉血栓形成加重或新发深静脉血栓的危险因素。

Risk factors for postoperative DVT exacerbation or new DVT in patients with spinal cord injury complicated with cervical fracture.

作者信息

Wang Haiying, Lv Bing, Li Wei, Xu Jingjing, Ma Ce

机构信息

Department of Orthopaedic Surgery, Baoding No.1 Central Hospital, Baoding, China.

Department of Ultrasound Medicine, Baoding No.1 Central Hospital, Baoding, China.

出版信息

Front Cardiovasc Med. 2024 Sep 30;11:1458941. doi: 10.3389/fcvm.2024.1458941. eCollection 2024.

Abstract

OBJECTIVE

To investigate the dynamic changes of perioperative deep venous thrombosis (DVT) in patients with spinal cord injury complicated with cervical fracture and analyze the risk factors of postoperative DVT exacerbation or new DVT.

METHODS

From January 2018 to December 2023, a total of 232 patients with spinal cord injury complicated with cervical fracture in our hospital were retrospectively analyzed. Ultrasonography of both lower limbs was performed before and after surgery. According to whether there was aggravation of DVT or new thrombosis, the group was divided into DVT exacerbation or new DVT group and non-DVT exacerbation group. Clinical data were used to study the dynamic changes of perioperative DVT. Logistic regression analysis and receiver operating characteristic (ROC) curve were used to explore the risk factors.

RESULTS

The DVT was found in 47 patients before surgery, including 26 cases of distal thrombus, 14 cases of mixed thrombus and 7 cases of proximal thrombus. Postoperative DVT increased to 81, including 31 distal thrombus, 35 mixed thrombus and 15 proximal thrombus. A total of 53 patients (22.8%, 53/232) experienced postoperative DVT exacerbation or new DVT. Logistic regression analysis revealed that age, American Spinal Injury Association (ASIA) score, time from injury to surgery, surgery time and blood loss were risk factors for postoperative DVT exacerbation.

CONCLUSIONS

In patients with spinal cord injury complicated with cervical fracture, the risk of postoperative DVT exacerbation is very high. Age, ASIA score A-B, time from injury to surgery, surgery time and blood loss were risk factors for postoperative DVT exacerbation or new DVT.

摘要

目的

探讨脊髓损伤合并颈椎骨折患者围手术期深静脉血栓形成(DVT)的动态变化,并分析术后DVT加重或新发DVT的危险因素。

方法

回顾性分析2018年1月至2023年12月我院收治的232例脊髓损伤合并颈椎骨折患者。术前、术后均行双下肢超声检查。根据DVT是否加重或有新血栓形成,将患者分为DVT加重或新发DVT组和非DVT加重组。采用临床资料研究围手术期DVT的动态变化。采用Logistic回归分析和受试者工作特征(ROC)曲线探讨危险因素。

结果

术前发现47例DVT患者,其中远端血栓26例,混合血栓14例,近端血栓7例。术后DVT增至81例,其中远端血栓31例,混合血栓35例,近端血栓15例。共有53例患者(22.8%,53/232)术后出现DVT加重或新发DVT。Logistic回归分析显示,年龄、美国脊髓损伤协会(ASIA)评分、受伤至手术时间、手术时间和失血量是术后DVT加重的危险因素。

结论

脊髓损伤合并颈椎骨折患者术后DVT加重风险很高。年龄、ASIA评分A - B、受伤至手术时间、手术时间和失血量是术后DVT加重或新发DVT的危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8ff6/11471601/593000020627/fcvm-11-1458941-g001.jpg

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