Huang An, Liu Xueqi, Gu An, Zhao Dan, Huang Cheng, Wang Lina
School of Medicine, Huzhou University, Huzhou, Zhejiang, China.
Centre for Health Management and Policy Research, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Digit Health. 2024 Oct 13;10:20552076241288651. doi: 10.1177/20552076241288651. eCollection 2024 Jan-Dec.
Mental health issues are highly prevalent in older adults with mild cognitive impairment (MCI). Digital Health Interventions (DHIs) for individuals with MCI have proven effective in improving cognitive function, but their impact on mental health has received less attention.
Reporting a protocol for a systematic review and meta-analysis to evaluate the effectiveness of DHIs for older adults with MCI, focusing on mental health outcomes both overall and within homogeneous subgroups.
A systematic review and meta-analysis of randomized controlled trials will be conducted, with searches performed in the Cochrane Library, PubMed, Embase, Web of Science, CINAHL, CNKI, and WanFang date from inception to March 2024. Mental health outcomes are the primary outcome. Risk of bias will be assessed with the Cochrane Collaboration tool, and evidence quality will be evaluated with Grading of Recommendations Assessment, Development, and Evaluation. If sufficient studies are available, subgroup analysis will assess variations based on population and intervention characteristics, including types and modalities of DHIs, intervention settings, session frequency, and duration, focusing on specific mental health outcomes and both short- and long-term effects. Additionally, sensitivity analysis and meta-regression analysis will identify sources of other potential heterogeneity.
The protocol will guide a systematic review and meta-analysis to determine the effectiveness of DHIs in improving mental health of older adults with MCI. This effort will enhance understanding and optimization of DHIs, vital for reducing mental health disparities and improving psychotherapy access for older adults with MCI.
CRD42024522342.
心理健康问题在患有轻度认知障碍（MCI）的老年人中非常普遍。针对MCI患者的数字健康干预（DHI）已被证明在改善认知功能方面有效，但其对心理健康的影响却较少受到关注。
报告一项系统评价和荟萃分析的方案，以评估DHI对患有MCI的老年人的有效性，重点关注总体心理健康结果以及同质亚组中的心理健康结果。
将对随机对照试验进行系统评价和荟萃分析，检索Cochrane图书馆、PubMed、Embase、科学网、CINAHL、中国知网和万方数据库，检索时间从建库至2024年3月。心理健康结果是主要结果。将使用Cochrane协作工具评估偏倚风险，并使用推荐分级评估、制定和评价系统评估证据质量。如果有足够的研究，亚组分析将根据人群和干预特征评估差异，包括DHI的类型和方式、干预环境、疗程频率和持续时间，重点关注特定的心理健康结果以及短期和长期影响。此外，敏感性分析和荟萃回归分析将确定其他潜在异质性的来源。
该方案将指导一项系统评价和荟萃分析，以确定DHI在改善患有MCI的老年人心理健康方面的有效性。这项工作将加强对DHI的理解和优化，这对于减少心理健康差异和改善患有MCI的老年人获得心理治疗的机会至关重要。
PROSPERO注册号：CRD42024522342。
