Filice G A, Van Etta L L, Darby C P, Fraser D W
Am J Epidemiol. 1986 Jan;123(1):128-36. doi: 10.1093/oxfordjournals.aje.a114206.
To describe the epidemiology of bacteremia in a large, well defined population, the authors reviewed medical records for residents of Charleston County, South Carolina, who had bacteria isolated from blood in the period 1974 to 1976. The incidence was 80 cases per 100,000 population per year. The most common organisms were Escherichia coli, Staphylococcus aureus, Klebsiella, and Streptococcus pneumoniae. The incidence was highest for neonates, infants, and those 70 years of age and older with annualized attack rates of 1,864,250, and 446 cases per 100,000 population, respectively. The incidence was 3.2 times higher for blacks than for whites and, within races, appeared to be independent of family income. Twenty-five per cent of patients had no clinically apparent focus of infection, 26% had urinary tract infection, and 17% had pneumonia. Thirty-nine per cent of cases were nosocomial, and 30% of patients died.
为描述一个大型、界定明确人群中菌血症的流行病学特征，作者回顾了南卡罗来纳州查尔斯顿县居民在1974年至1976年期间血液中分离出细菌的病历。发病率为每年每10万人口80例。最常见的病原体为大肠杆菌、金黄色葡萄球菌、克雷伯菌属和肺炎链球菌。新生儿、婴儿以及70岁及以上人群的发病率最高，年化发病率分别为每10万人口1864例、250例和446例。黑人的发病率比白人高3.2倍，且在各种族内部，发病率似乎与家庭收入无关。25%的患者没有临床明显的感染病灶，26%有尿路感染，17%有肺炎。39%的病例为医院感染，30%的患者死亡。
