Postgraduate Program in Dentistry and Health, School of Dentistry, Universidade Federal da Bahia, Salvador, Bahia, Brazil.
Department of Oral Pathology, School of Dentistry, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Head Neck Pathol. 2024 Oct 15;18(1):98. doi: 10.1007/s12105-024-01703-9.
Metastases in the oral and maxillofacial region, particularly in soft tissues, are exceedingly rare. Such metastases can present as swelling in older individuals, especially in the tongue and gingiva. Furthermore, colorectal metastases at this site are commonly found in the mandible and gingiva and usually share the same morphology as the primary tumor. Herein, we report the case of a 61-year-old woman with a metastatic nodule in the tongue covered by normal mucosa. The clinical, histopathological, and immunohistochemical findings were essential for the final diagnosis of colorectal metastasis, consistent with adenocarcinoma with mucinous differentiation and intestinal phenotype. Metastases of colorectal adenocarcinoma to the tongue are rare but should be included in the differential diagnosis of nodular lesions at this site. The diagnosis can therefore be made based on meticulous clinical and histopathological examination complemented by immunohistochemistry.
口腔颌面部转移瘤，特别是软组织转移瘤极为罕见。这些转移瘤可表现为老年人的肿胀，特别是在舌和牙龈。此外，结直肠转移瘤常发生于下颌骨和牙龈，且通常与原发性肿瘤具有相同的形态。在此，我们报告了一例 61 岁女性舌部有一被正常黏膜覆盖的转移结节。临床、组织病理学和免疫组织化学检查对最终诊断为结直肠转移瘤具有重要意义，符合黏液腺癌和肠型。结直肠腺癌转移至舌部较为罕见，但应纳入该部位结节性病变的鉴别诊断。因此，基于细致的临床和组织病理学检查，并辅以免疫组织化学，即可做出诊断。
