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外伤性虹膜炎的发病率、机制及临床特征:一项基于人群的分析

Incidence, Mechanisms, and Clinical Characteristics of Traumatic Iritis: A Population-Based Analysis.

作者信息

Wang Kenny Y, Kim B Michelle, Xu Timothy T, Reynolds Margaret M, Hodge David O, Smith Wendy M

机构信息

Alix School of Medicine, Mayo Clinic, Rochester, Minnesota, USA.

Department of Ophthalmology, Mayo Clinic, Rochester, Minnesota, USA.

出版信息

Ocul Immunol Inflamm. 2025 Apr;33(3):378-384. doi: 10.1080/09273948.2024.2413899. Epub 2024 Oct 15.

Abstract

PURPOSE

To describe the incidence, mechanisms, and clinical characteristics of patients diagnosed with traumatic iritis in a U.S. Midwestern county population.

METHODS

Retrospective population-based cohort of all residents of Olmsted County, Minnesota diagnosed with traumatic iritis from January 1, 2006, to December 31, 2015. The medical records of patients with traumatic iritis were identified using the Rochester Epidemiology Project database, which contains virtually all medical care in the county. Medical records were reviewed for demographics, presentation, and follow-up data. Incidence rates were calculated per 100,000 per year.

RESULTS

There were 156 incident diagnoses of traumatic iritis during the 10-year study period, yielding an age- and sex-adjusted incidence rate of 10.7 per 100,000 per year. Traumatic iritis disproportionately occurred in male ( < 0.001) and Black ( < 0.001) patients. The mean age of diagnosis was 33 years (range: 4-96 years), mean number of traumatic iritis-specific follow-up visits was 2.1 (range: 0-26), and median duration of traumatic iritis-specific follow-up was 11 days (range: 1 day-1.6 years). There were 155 (99.4%) patients with unilateral disease. The most frequent mechanisms of traumatic iritis were sports-related ( = 29, 18.6%), assault-related ( = 23, 14.7%), scratch ( = 22, 14.1%), and work-related ( = 21, 13.5%) injuries. The mean initial and final best-corrected visual acuity (BCVA) of the affected eye was 20/40 and 20/30, respectively. Loss of follow-up was more frequently observed in Black patients ( < 0.001) and patients with smoking history ( = 0.004).

CONCLUSION

Traumatic iritis was most frequently observed in younger males and Black patients. Common mechanisms included sports, assault, scratch, and work-related injuries.

摘要

目的

描述美国中西部一个县人群中诊断为外伤性虹膜炎患者的发病率、发病机制及临床特征。

方法

对明尼苏达州奥尔姆斯特德县2006年1月1日至2015年12月31日期间诊断为外伤性虹膜炎的所有居民进行基于人群的回顾性队列研究。利用罗切斯特流行病学项目数据库识别外伤性虹膜炎患者的病历,该数据库包含了该县几乎所有的医疗记录。对病历进行人口统计学、临床表现及随访数据的审查。计算每年每10万人的发病率。

结果

在10年研究期间有156例外伤性虹膜炎确诊病例,年龄和性别调整后的发病率为每年每10万人10.7例。外伤性虹膜炎在男性(<0.001)和黑人(<0.001)患者中更为常见。诊断时的平均年龄为33岁(范围:4 - 96岁),外伤性虹膜炎特异性随访的平均次数为2.1次(范围:0 - 26次),外伤性虹膜炎特异性随访的中位持续时间为11天(范围:1天 - 1.6年)。有155例(99.4%)患者为单眼患病。外伤性虹膜炎最常见的发病机制是与运动相关(n = 29,18.6%)、与袭击相关(n = 23,14.7%)、擦伤(n = 22,14.1%)及与工作相关(n = 21,13.5%)的损伤。患眼的初始和最终最佳矫正视力(BCVA)分别平均为20/40和20/30。黑人患者(<0.001)和有吸烟史的患者(P = 0.004)失访情况更为常见。

结论

外伤性虹膜炎在年轻男性和黑人患者中最为常见。常见发病机制包括运动、袭击、擦伤及与工作相关的损伤。

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