Moore J R
Can J Surg. 1986 Jan;29(1):25-8.
The records of 1030 patients with gastric carcinoma seen between 1941 and 1970 were analysed. A 10-year follow-up was available for 1024. The overall operability and resectability rates were 80.9% and 53.5% respectively, and in the two decades 1951 to 1960 and 1961 to 1970, the rates increased significantly, as did the subtotal gastrectomy rate of 46.9%. Subtotal resection for cure was done in 59.5%, and for palliation in 40.5%. Fifty-six patients underwent a total gastrectomy. There was no significant increase in consecutive decades in either overall 5-year survival or survival following subtotal gastrectomy. The 5- and 10-year survival rates of 15.1% and 6.6%. Of the 5-year survivors, 54% had no lymphnode involvement and 35.2% had nodes positive for tumour spread. Gastroesophagectomy was associated with a high morbidity and extremely low survival. Of 56 patients having a total gastrectomy, 37 lived 1 year or more while only 5 survived 5 or more years. Linitis plastica occurred with equal frequency in men and women. Operability and resectability rates were lower and there was a 90.6% 1-year death rate.
对1941年至1970年间收治的1030例胃癌患者的病历进行了分析。1024例患者有10年的随访资料。总体可手术率和可切除率分别为80.9%和53.5%，在1951年至1960年以及1961年至1970年这两个十年中，这些比率显著上升，46.9%的胃次全切除率也同样如此。根治性胃次全切除占59.5%，姑息性胃次全切除占40.5%。56例患者接受了全胃切除术。总体5年生存率以及胃次全切除术后的生存率在连续几十年中均无显著提高。5年和10年生存率分别为15.1%和6.6%。在5年存活者中，54%无淋巴结受累，35.2%的淋巴结有肿瘤转移阳性。胃食管切除术的发病率高且生存率极低。在56例接受全胃切除术的患者中，37例存活1年或更长时间，而只有5例存活5年或更长时间。皮革胃在男性和女性中的发生率相同。可手术率和可切除率较低，1年死亡率为90.6%。
