Lewis Joshua E, Patel Manav M, Lim Shawn E, Wolf Steven E, Song Juquan
John Sealy School of Medicine, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-1317, USA.
John Sealy School of Medicine, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555-1317, USA.
J Pediatr Surg. 2025 Jan;60(1):161973. doi: 10.1016/j.jpedsurg.2024.161973. Epub 2024 Sep 27.
Pediatric burns present a significant global health challenge, particularly in low- and middle-income countries (LMICs). Despite this burden, few studies have explored global sex-based differences in pediatric burns. This study aims to describe pediatric burn incidence, burn care facilities' capacities, and burn outcomes with a focus on sex, comparing LMICs to HICs.
This study utilizes the World Health Organization's (WHO) Global Burn Registry (GBR) to analyze pediatric burn cases from 2018 to 2022, examining patient demographics, causes of burns, burn care facilities' capacities, and burn outcomes in relation to sex. Statistical analysis was done by chi-square and logistic regression.
It was found that female patients were less likely than males to undergo surgical treatment during their hospital stay in low-income countries (adjusted odd ratios = 0.86, 95% CI: 0.45-1.26; p = 0.168) and middle-income countries (adjusted odd ratios = 0.72, 95% Cl: 0.52-0.95; p = 0.002). Additionally, females in both low- (adjusted odd ratios = 2.23, 95% Cl: 1.12-3.53; p = 0.045) and middle-income countries (adjusted odd ratios = 1.72, 95% Cl: 1.12-2.95; p < 0.001) exhibited higher odds of discharging with disability compared to males.
Sex-based differences persist in pediatric burn epidemiology and treatment outcomes. Addressing these differences involves sex-sensitive strategies to mitigate the burden of pediatric burns, particularly in vulnerable populations in low- and middle-income countries.
Retrospective observational study.
Level III evidence.
儿童烧伤是一项重大的全球健康挑战，在低收入和中等收入国家（LMICs）尤为如此。尽管负担沉重，但很少有研究探讨全球儿童烧伤的性别差异。本研究旨在描述儿童烧伤发病率、烧伤护理设施的能力以及烧伤结局，并重点关注性别，比较低收入和中等收入国家与高收入国家（HICs）的情况。
本研究利用世界卫生组织（WHO）的全球烧伤登记处（GBR）分析2018年至2022年的儿童烧伤病例，研究患者人口统计学特征、烧伤原因、烧伤护理设施的能力以及与性别相关的烧伤结局。采用卡方检验和逻辑回归进行统计分析。
研究发现，在低收入国家（调整后的比值比 = 0.86，95%置信区间：0.45 - 1.26；p = 0.168）和中等收入国家（调整后的比值比 = 0.72，95%置信区间：0.52 - 0.95；p = 0.002），女性患者在住院期间接受手术治疗的可能性低于男性。此外，在低收入国家（调整后的比值比 = 2.23，95%置信区间：1.12 - 3.53；p = 0.045）和中等收入国家（调整后的比值比 = 1.72，95%置信区间：1.12 - 2.95；p < 0.001），女性患者出院时伴有残疾的几率均高于男性。
儿童烧伤流行病学和治疗结局方面的性别差异依然存在。解决这些差异需要采取对性别敏感的策略，以减轻儿童烧伤负担，特别是在低收入和中等收入国家的弱势群体中。
回顾性观察研究。
三级证据。
