AlSahman Lujain, AlBagieh Hamad, AlSahman Roba
Oral Medicine and Diagnostic Sciences Department, College of Dentistry, King Saud University Riyadh, Riyadh 57448, Saudi Arabia.
Faculty of Dentistry, Royal College of Surgeons, D02 YN77 Dublin, Ireland.
Diagnostics (Basel). 2024 Sep 30;14(19):2183. doi: 10.3390/diagnostics14192183.
(1) Background: Temporomandibular disorders (TMD) signs and symptoms affect the quality of life of patients because they impose an incapacity to participate in daily life activities, causing both physical and psychological discomfort. This review aims to provide the most accurate, comprehensive, and up-to-date description of all information available regarding OHRQoL in TMD. (2) Methods: A systematic search of articles from January 2013 till August 2023 was performed on five databases to identify articles, including TMD and oral health-related quality of life. Two calibrated reviewers performed the search following inclusion and exclusion criteria. A manual search of reference articles was also performed. The data were analyzed qualitatively by combining a meta-analysis and GRADE evidence. The Newcastle-Ottawa scale for cross-sectional and case-control studies was utilized to assess the quality of the included studies. (3) Results: The initial search consisted of 738 articles without the removal of duplicates. Fifteen articles were included in this systematic review, and ten were included in the meta-analysis. Almost all the included observational studies reported poor OHRQoL among patients with different types of TMD. The results of the meta-analysis with a standard mean difference (SMD) and that included seven studies suggest high heterogeneity with I = 99%, SMD (95% CI) = 3.18 (1.90, 4.46), -value < 0.01. The odds ratio analyzed for three included articles in the meta-analysis reported statistical significance (-value < 0.01) with OR = 8.21 (2.39, 28.25) and a heterogeneity of 86%. The certainty of evidence by GRADE resulted in a downgraded level of evidence, indicating that the OHRQoL of TMD patients may differ slightly from the healthy controls. (4) Conclusions: The impact of OHRQoL on the TMD was deemed to be significant. Overall, the OHRQoL is low for any type and intensity of pain among TMD patients and controls.
(1) 背景：颞下颌关节紊乱病（TMD）的体征和症状会影响患者的生活质量，因为它们导致患者无法参与日常生活活动，造成身体和心理上的不适。本综述旨在提供有关TMD患者口腔健康相关生活质量（OHRQoL）的所有可用信息的最准确、全面和最新描述。(2) 方法：在五个数据库中对2013年1月至2023年8月的文章进行系统检索，以识别包括TMD和口腔健康相关生活质量的文章。两名经过校准的评审员按照纳入和排除标准进行检索。还对手参考文献进行了手动检索。通过结合荟萃分析和GRADE证据对数据进行定性分析。采用纽卡斯尔-渥太华横断面和病例对照研究量表来评估纳入研究的质量。(3) 结果：初始检索包括738篇文章，未去除重复项。本系统综述纳入了15篇文章，荟萃分析纳入了10篇文章。几乎所有纳入的观察性研究均报告不同类型TMD患者的OHRQoL较差。一项纳入七项研究的采用标准均数差（SMD）的荟萃分析结果显示，异质性较高，I = 99%，SMD（95% CI） = 3.18（1.90，4.46），P值<0.01。对荟萃分析中纳入的三篇文章分析的比值比报告具有统计学意义（P值<0.01），OR = 8.21（2.39，28.25），异质性为86%。GRADE证据的确定性导致证据水平降级，表明TMD患者的OHRQoL可能与健康对照略有不同。(4) 结论：OHRQoL对TMD的影响被认为是显著的。总体而言，TMD患者和对照中任何类型和强度疼痛的OHRQoL都较低。
