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确定原发性面肌痉挛治疗中的预后因素:临床结果与并发症。文献综述。

Determining prognostic factors in the treatment of primary hemifacial spasm: Clinical outcomes and complications. A literature review.

作者信息

Acevedo-González Juan Carlos, Taub-Krivoy Alex, Sierra-Peña Julian Alfonso, Lizarazo Julian Geronimo

机构信息

Neurosurgeon Specialized in Functional Neurosurgery and Stereotaxic Surgery, Pain, and Spasticity Management, Full Professor at the Faculty of Medicine, Pontifical Javeriana University, San Ignacio University Hospital, Bogotá, Colombia.

Coordinator of the Research Group in Neurosurgery, Pontifical Javeriana University, Bogotá, Colombia.

出版信息

World Neurosurg X. 2024 Sep 28;25:100406. doi: 10.1016/j.wnsx.2024.100406. eCollection 2025 Jan.

DOI:10.1016/j.wnsx.2024.100406
PMID:39411270
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11474211/
Abstract

OBJECTIVE

Primary Hemifacial Spasm (PHFS) significantly impacts quality of life, necessitating effective treatment like microvascular decompression of the facial nerve. This study aims to identify prognostic factors related to surgical treatment to enhance outcomes and minimize complications. A systematic review of literature from the past five years was conducted.

METHODS

Following PRISMA guidelines, we systematically searched databases like PubMed, Embase, Scopus, Ovid, EBSCO, and Cochrane using keywords such as 'Hemifacial spasm,' 'Microvascular decompression,' 'Neurovascular conflict,' and 'Surgical techniques.' The search spanned January 2018 to November 2023. The 'Rayyan' program facilitated data compilation. Each author reviewed abstracts, applying inclusion criteria like systematic reviews, clinical trials, observational studies, and case series, while excluding theoretical or non-English articles.

RESULTS

Of 26 selected articles, those solely addressing PHFS treatment with botulinum toxin and lacking surgical procedure data were excluded. Thus, our analysis focused on 16 articles, including meta-analyses, systematic reviews, clinical trials, and observational studies.

DISCUSSION

Microvascular decompression at the cerebellar pontine angle is the mainstay treatment for hemifacial spasm. Despite limited statistically significant prognostic factors in the literature, overarching recommendations aim to improve outcomes, minimize complications, and prevent recurrences. Key considerations include surgeon expertise, precise techniques, thorough nerve exploration, identifying the conflict's cause, and intraoperative monitoring.

CONCLUSIONS

PHFS significantly impacts patients' lives, necessitating timely surgical intervention if initial treatments fail. While statistically significant prognostic factors may be lacking, this study highlights crucial considerations for successful treatment.

摘要

目的

原发性面肌痉挛(PHFS)严重影响生活质量,需要进行有效的治疗,如面神经微血管减压术。本研究旨在确定与手术治疗相关的预后因素,以提高治疗效果并减少并发症。我们对过去五年的文献进行了系统综述。

方法

遵循PRISMA指南,我们使用“面肌痉挛”、“微血管减压术”、“神经血管冲突”和“手术技术”等关键词,在PubMed、Embase、Scopus、Ovid、EBSCO和Cochrane等数据库中进行系统检索。检索时间跨度为2018年1月至2023年11月。“Rayyan”程序协助进行数据整理。每位作者对摘要进行评审,应用系统评价、临床试验、观察性研究和病例系列等纳入标准,同时排除理论性或非英文文章。

结果

在26篇入选文章中,那些仅涉及肉毒杆菌毒素治疗PHFS且缺乏手术操作数据的文章被排除。因此,我们的分析聚焦于16篇文章,包括荟萃分析、系统评价、临床试验和观察性研究。

讨论

小脑脑桥角微血管减压术是面肌痉挛的主要治疗方法。尽管文献中具有统计学意义的预后因素有限,但总体建议旨在改善治疗效果、减少并发症并预防复发。关键考虑因素包括外科医生的专业技能、精确的技术、彻底的神经探查、确定冲突原因以及术中监测。

结论

PHFS严重影响患者生活,如果初始治疗失败,需要及时进行手术干预。虽然可能缺乏具有统计学意义的预后因素,但本研究强调了成功治疗的关键考虑因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2247/11474211/4743d33d4a35/gr9.jpg
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本文引用的文献

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Surgical treatment of hemifacial spasms: how to predict failure and complications through a series of 200 patients.面肌痉挛的手术治疗:通过 200 例患者系列研究预测失败和并发症的方法。
Neurochirurgie. 2023 Nov;69(6):101498. doi: 10.1016/j.neuchi.2023.101498. Epub 2023 Sep 21.
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Predictors of Multi-Vessel Identification, Outcome, and Optimal Surgical Timing for Microvascular Decompression in Hemifacial Spasm.预测面肌痉挛微血管减压术中多血管识别、预后及最佳手术时机的因素。
Clin Neurol Neurosurg. 2023 Oct;233:107841. doi: 10.1016/j.clineuro.2023.107841. Epub 2023 Jun 22.
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Different MRI-based methods for the diagnosis of neurovascular compression in trigeminal neuralgia or hemifacial spasm: A network meta-analysis.
不同基于 MRI 的三叉神经痛或面肌痉挛神经血管压迫诊断方法的网络荟萃分析。
J Clin Neurosci. 2023 Feb;108:19-24. doi: 10.1016/j.jocn.2022.12.016. Epub 2022 Dec 26.
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Factors Related to Hemifacial Spasm Recurrence in Patients Undergoing Microvascular Decompression-A Systematic Review and Meta-Analysis.微血管减压术治疗面肌痉挛患者复发相关因素的系统评价和Meta分析
Brain Sci. 2022 Apr 29;12(5):583. doi: 10.3390/brainsci12050583.
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Influence of Minimum Alveolar Concentration and Inhalation Duration of Sevoflurane on Facial Nerve Electromyography in Hemifacial Spasm: A Randomized Controlled Trial.七氟醚最低肺泡浓度和吸入时间对面肌痉挛面神经肌电图的影响:一项随机对照试验。
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Usefulness of intraoperative monitoring in microvascular decompression for hemifacial spasm: a systematic review and meta-analysis.术中监测在面肌痉挛微血管减压术中的应用:系统评价和荟萃分析。
Br J Neurosurg. 2022 Jun;36(3):346-357. doi: 10.1080/02688697.2022.2049701. Epub 2022 Mar 22.
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Neurosurg Rev. 2022 Jun;45(3):2201-2210. doi: 10.1007/s10143-022-01739-x. Epub 2022 Jan 20.
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