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印度黑热病（内脏利什曼病）病死率上升：对黑热病消除计划的意外挑战？

Rising case-fatality rate of kala-azar (visceral leishmaniasis) in India: An unexpected challenge to the kala-azar elimination program?

作者信息

Mayilsamy Muniaraj, Veeramanoharan Rajamannar, Rajaiah Paramasivan

机构信息

ICMR-Vector Control Research Centre Field Station, Madurai, Tamil Nadu, India.

出版信息

Trop Parasitol. 2024 Jul-Dec;14(2):117-120. doi: 10.4103/tp.tp_57_23. Epub 2024 Sep 3.

DOI:10.4103/tp.tp_57_23
PMID:39411679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11473009/
Abstract

The target of kala-azar elimination was initially set in 2010 and was later extended several times to finally be fixed in 2020, which also passed without success. However, in 2022, India had come very close to complete elimination by achieving a 98.7% decline in kala-azar cases. While, at the final moments of achieving the long-awaited target of elimination of kala-azar from India, the unexpected rise in the case-fatality rate from 2017 needs to be addressed.

摘要

黑热病消除目标最初于2010年设定，后来多次延期，最终确定在2020年，但也未成功实现。然而，在2022年，印度已非常接近完全消除，黑热病病例下降了98.7%。同时，在实现从印度消除黑热病这一期待已久的目标的最后时刻，2017年以来病死率意外上升的问题需要得到解决。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eda/11473009/7fba33f6b6c3/TP-14-117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eda/11473009/7fba33f6b6c3/TP-14-117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0eda/11473009/7fba33f6b6c3/TP-14-117-g001.jpg

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本文引用的文献

1
Impact of COVID-19 lockdown during 2020 on the occurrence of vector-borne diseases in India.2020 年新冠疫情封锁对印度虫媒传染病发生的影响。
J Vector Borne Dis. 2023 Apr-Jun;60(2):207-210. doi: 10.4103/0972-9062.364762.
2
Accelerating kala-azar elimination in India.加速印度消除黑热病进程。
Indian J Med Res. 2020 Dec;152(6):538-540. doi: 10.4103/ijmr.IJMR_841_19.
3
The lost hope of elimination of Kala-azar (visceral leishmaniasis) by 2010 and cyclic occurrence of its outbreak in India, blame falls on vector control practices or co-infection with human immunodeficiency virus or therapeutic modalities?
到2010年消除黑热病（内脏利什曼病）的希望破灭，且该病在印度周期性爆发，这该归咎于病媒控制措施、与人类免疫缺陷病毒的共同感染还是治疗方式呢？
Trop Parasitol. 2014 Jan;4(1):10-9. doi: 10.4103/2229-5070.129143.
4
Occurrence & significance of kala-azar in Bhutan.黑热病在不丹的发生情况及意义。
Indian J Med Res. 2010 Sep;132:337-8.
5
Can visceral leishmaniasis be eliminated from Asia?内脏利什曼病能在亚洲被消灭吗？
J Vector Borne Dis. 2008 Jun;45(2):105-11.
6
Leishmaniasis and poverty.利什曼病与贫困
Trends Parasitol. 2006 Dec;22(12):552-7. doi: 10.1016/j.pt.2006.09.004. Epub 2006 Oct 4.
7
Serious underreporting of visceral leishmaniasis through passive case reporting in Bihar, India.印度比哈尔邦通过被动病例报告对内脏利什曼病的严重漏报情况。
Trop Med Int Health. 2006 Jun;11(6):899-905. doi: 10.1111/j.1365-3156.2006.01647.x.