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日间手术与非工作时间手术治疗慢性硬脑膜下血肿。

Daytime versus out-of-hours surgery for Chronic Subdural Hematoma.

机构信息

Department of Neurosurgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Department of Neurosurgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

出版信息

J Clin Neurosci. 2024 Nov;129:110863. doi: 10.1016/j.jocn.2024.110863. Epub 2024 Oct 15.

Abstract

Chronic Subdural Hematoma (CSDH) is one of the most common neurosurgical pathologies. Due to an elderly demographic with increasing co-morbidities, surgery is often deferred out of hours. This may reduce complication risk, but increases length of stay and may compromise patient care due to delayed surgery. We performed a retrospective service evaluation of CSDH patients undergoing primary surgery (September 2021-September 2023) at a tertiary neurosciences centre. Out of hours (OOH) was defined as an operation start time outside 8 am-8 pm. Primary outcome was recurrence requiring repeat surgery. Secondary outcomes included complications, thromboembolic events (DVT/PE), length of stay, and in hospital mortality. Differences were assessed using Chi-Squared tests and Student's t-tests. A total of 263 patients were included (200 (76.0 %) male, mean age 75.0 ± 11.3 yrs). Median time from admission to surgery was 37 h (IQR 14-71.5 h). In total, 49.8 % (131/263) of operations took place OOH. There were no significant differences in baseline characteristics between the two groups. At a median follow-up of 9.2 months (IQR 4.8-13.2 months) there was no difference in recurrence rates between OOH and in hours groups (14.5 % vs. 17.7 %, p = 0.483). There was no difference in complication rates (13.7 % vs 16.2 %, p = 0.585), thromboembolic events (3.8 % vs 3.1 %, p = 0.743), length of stay (mean 15.9 vs 15.2 days, p = 0.787), or in-hospital mortality (2.3 % vs 3.1 %, p = 0.483). OOH surgery for CSDH surgery is safe, does not appear to affect complications, recurrence, or mortality, and should be considered in appropriately selected cases.

摘要

慢性硬脑膜下血肿(CSDH)是最常见的神经外科疾病之一。由于老年人口中合并症的增加,手术通常在非工作时间进行。这可能会降低并发症的风险,但会延长住院时间,并可能由于手术延迟而影响患者的护理。我们对一家三级神经科学中心的 CSDH 患者进行了原发性手术(2021 年 9 月至 2023 年 9 月)的回顾性服务评估。非工作时间(OOH)定义为手术开始时间不在上午 8 点至晚上 8 点之间。主要结果是需要再次手术的复发。次要结果包括并发症、血栓栓塞事件(DVT/PE)、住院时间和住院死亡率。差异采用卡方检验和学生 t 检验进行评估。共纳入 263 例患者(200 例[76.0%]为男性,平均年龄 75.0±11.3 岁)。从入院到手术的中位时间为 37 小时(IQR 14-71.5 小时)。总共有 49.8%(131/263)的手术在 OOH 进行。两组患者的基线特征无显著差异。在中位随访 9.2 个月(IQR 4.8-13.2 个月)时,OOH 组和非 OOH 组的复发率无差异(14.5% vs. 17.7%,p=0.483)。并发症发生率(13.7% vs. 16.2%,p=0.585)、血栓栓塞事件(3.8% vs. 3.1%,p=0.743)、住院时间(平均 15.9 天 vs. 15.2 天,p=0.787)或住院死亡率(2.3% vs. 3.1%,p=0.483)无差异。对于 CSDH 手术,OOH 手术是安全的,似乎不会影响并发症、复发或死亡率,并且在适当选择的情况下应予以考虑。

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