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医疗补助扩大计划对肺癌患者辅助化疗接受情况的作用

The Role of Medicaid Expansion on the Receipt of Adjuvant Chemotherapy in Patients With Lung Cancer.

作者信息

Rshaidat Hamza, Mack Shale J, Koeneman Scott H, Martin Jonathan, Whitehorn Gregory L, Madeka Isheeta, Gordon Sarah W, Okusanya T Olugbenga T

机构信息

Department of Surgery, Division of Esophageal and Thoracic Surgery, Thomas Jefferson University Hospital, Philadelphia, PA, 19107.

Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, 19107.

出版信息

Clin Lung Cancer. 2025 Mar;26(2):131-139. doi: 10.1016/j.cllc.2024.09.007. Epub 2024 Sep 24.

Abstract

OBJECTIVE

We aimed to utilize a nationally representative database to study the effect of Medicaid expansion on the receipt of adjuvant chemotherapy in eligible patients.

MATERIALS AND METHODS

Retrospective review of the National Cancer Database (NCDB) was performed between 2006 and 2019. Patients with clinical T1-T3, N1, and M0 were included. Patients with nodal disease or tumors > 4 cm were eligible for adjuvant therapy. Demographic and clinical information were collected. A difference-in-difference analysis was performed to compare changes in the rate of adjuvant chemotherapy.

RESULTS

Total 9954 eligible patients were treated in states that expanded Medicaid coverage in January 2014 or later, with 4809 patients treated in the pre-expansion years (2012-2013) and 5145 patients treated in the postexpansion years (2017-2018). Following Medicaid expansion, eligible patients were more likely to receive adjuvant therapy (70.2% vs. 62.3%; P < .001). Compared with the pre-expansion period, patients who received adjuvant therapy were more likely to use Medicaid insurance postexpansion (7.8% vs. 5%, P < .001). Among patients using Medicaid coverage only, a greater percentage started adjuvant therapy within 8 weeks of resection following Medicaid expansion (46.6% vs. 38.3%, P = .048). The observed difference-in-difference in the change in adjuvant therapy rate from the pre-expansion period to the postexpansion period between expansion and nonexpansion states was 1.25% (95% Bootstrap CI -0.36% to -3.18%). There was a modest survival benefit in expansion states postexpansion.

CONCLUSION

Medicaid expansion appears to be associated with increased access to care, as shown by the increased receipt of adjuvant systemic therapy in eligible patients.

摘要

目的

我们旨在利用一个具有全国代表性的数据库,研究医疗补助扩大对符合条件患者接受辅助化疗的影响。

材料与方法

对2006年至2019年期间的国家癌症数据库(NCDB)进行回顾性分析。纳入临床分期为T1-T3、N1和M0的患者。有淋巴结疾病或肿瘤直径>4 cm的患者符合辅助治疗条件。收集人口统计学和临床信息。采用差异分析比较辅助化疗率的变化。

结果

在2014年1月或之后扩大医疗补助覆盖范围的州,共治疗了9954例符合条件的患者,其中4809例患者在扩大前的年份(2012-2013年)接受治疗,5145例患者在扩大后的年份(2017-2018年)接受治疗。医疗补助扩大后,符合条件的患者更有可能接受辅助治疗(70.2%对62.3%;P<.001)。与扩大前相比,接受辅助治疗的患者在扩大后更有可能使用医疗补助保险(7.8%对5%,P<.001)。在仅使用医疗补助覆盖的患者中,医疗补助扩大后,更大比例的患者在切除后8周内开始辅助治疗(46.6%对38.3%,P = .048)。扩大和未扩大医疗补助的州之间,从扩大前到扩大后辅助治疗率变化的观察到的差异为1.25%(95%自展置信区间为-0.36%至-3.18%)。扩大医疗补助的州在扩大后有适度的生存获益。

结论

如符合条件的患者辅助全身治疗的接受率增加所示,医疗补助扩大似乎与获得医疗服务的机会增加有关。

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