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腮腺切除术的修正——基于单中心 10 年随访的手术适应证分析及治疗结果。

Revision parotidectomy - analysis of indications for the procedure and treatment results based on 10 years of follow-up in a single center.

机构信息

Otorhinolaryngology Department Head and Neck Surgery, Medical University of Warsaw, Poland.

Student Scientific Research Group at the Otorhinolaryngology Department Head and Neck Surgery, Medical University of Warsaw, Poland.

出版信息

Otolaryngol Pol. 2024 Oct 31;78(5):24-32. doi: 10.5604/01.3001.0054.6857.

DOI:10.5604/01.3001.0054.6857
PMID:39417261
Abstract

<b>Introduction:</b> Surgical removal of recurrent parotid gland tumours is the first-line treatment but presents an increased risk of facial nerve injury and a considerable re-recurrence failure rate.<b>Aim:</b> Identification of individuals exposed to a higher risk of re-procedure, raising awareness in the preoperative setting, and proposing an optimal follow-up.<b>Methods:</b> The retrospective review included 72 patients treated with revision surgery in a single centre. The demographics, clinicopathologic variables, and operative details were analysed.<b>Results:</b> Recurrent pleomorphic adenoma (PA) was the main reason for reoperation (66.7%), followed by new monomorphic adenoma (13.9%), resection extension (12.5%), and malignancy recurrence (6.9%). Time to revision surgery was on average 68.6 months and was the shortest for extended resection cases (average 1.9 months). The period was substantially longer in recurrent PA (90.8 months). The final facial nerve function according to the House-Brackmann scale (HBS) decreased in 37% of patients after reoperation. The number of recurrences per patient ranged from one in 61% of cases to eight in a solitary case.<b>Conclusions:</b> The rate of revision parotid surgery was 8.4%. Negative margins at the first resection were not of protective significance. Recurrent PA was the main cause of revision surgery and over one-third of this cohort had a subsequent relapse. As many as 37% of patients experienced a decrease in facial nerve function following revision surgery.

摘要

<b>引言:</b>手术切除复发性腮腺肿瘤是一线治疗方法,但会增加面神经损伤的风险,且有相当高的再复发失败率。<b>目的:</b>识别出具有更高再手术风险的个体,提高术前意识,并提出最佳的随访建议。<b>方法:</b>本回顾性研究纳入了在单中心接受再次手术治疗的 72 例患者。分析了患者的人口统计学、临床病理学变量和手术细节。<b>结果:</b>复发性多形性腺瘤(PA)是再次手术的主要原因(66.7%),其次是新的单形性腺瘤(13.9%)、切除范围扩大(12.5%)和恶性肿瘤复发(6.9%)。再次手术的平均时间为 68.6 个月,扩展切除病例的时间最短(平均 1.9 个月)。复发性 PA 的时间明显更长(90.8 个月)。根据 House-Brackmann 量表(HBS)评估,术后 37%的患者面神经功能下降。每位患者的复发次数从 61%的病例中一例到一例中八例不等。<b>结论:</b>再次行腮腺手术的比例为 8.4%。初次切除时的阴性切缘并无保护意义。复发性 PA 是再次手术的主要原因,超过三分之一的患者发生了后续复发。多达 37%的患者在再次手术后面神经功能下降。

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