Rouyer F, Simmler M C, Johnsson C, Vergnaud G, Cooke H J, Weissenbach J
Nature. 1986;319(6051):291-5. doi: 10.1038/319291a0.
Three independent pseudoautosomal loci are linked to sex determination at frequencies which define a gradient of linkage. The segregation patterns of these loci indicate that X/Y recombination results from a single obligatory meiotic crossing-over in the pseudoautosomal region. Recombination in male germ cells in the terminal regions of the short arms of the X and Y chromosomes in 10-fold greater than between the same regions of the X chromosomes in female germ cells.
三个独立的拟常染色体基因座与性别决定相关联,其频率定义了一个连锁梯度。这些基因座的分离模式表明,X/Y重组是由拟常染色体区域中一次 obligatory 减数分裂交叉导致的。在雄性生殖细胞中,X和Y染色体短臂末端区域的重组频率比雌性生殖细胞中X染色体相同区域之间的重组频率高10倍。 (注:“obligatory”这里可能是个特定术语,不太明确其准确含义,暂直译为“ obligatory” )