Department of Physiology, College of Medicine, King Saud University, Riyadh - Arábia Saudita.
Department of Exercise Physiology, College of Sport Sciences and Physical Activity, King Saud University, Riyadh - Arábia Saudita.
Arq Bras Cardiol. 2024 Sep;121(5):e20220780. doi: 10.36660/abc.20220780.
Visceral adipose tissue (VAT) may be a specific modifiable contributor to body composition-related autonomic impairment.
To compare heart rate variability (HRV) between groups stratified by visceral fat rating (VFR) and compare associations between HRV and body composition metrics.
A cross-sectional study was conducted on healthy men (n=99,age=37.8±13.4 years, body mass index [BMI]=26.9±4.6 kg/m2). HRV was derived from 5-minute electrocardiographic recordings. Body composition (body fat percentage, VFR, and muscle mass to visceral fat ratio [MMVFR]) was estimated using tetrapolar bioelectrical impedance analysis. Participants were categorized into groups according to VFR: G1 (VFR=1-8); G2(VFR=9-12); and G3(VFR>12). Age-adjusted comparisons were made between groups. Independent associations were quantified with multiple linear regressions. P <0.05 was significant.
Root-mean square of successive differences (RMSSD) and standard deviation of normal RR intervals (SDNN) were higher for G1 vs. G2 and G3 (p<0.05). Low-frequency power (LF) was higher in G1 than in G2 (p<0.05). VFR and MMVFR were negatively associated with SDNN, RMSSD, LF, and HF (p<0.05). After adjusting for age, BMI, and systolic and diastolic blood pressure, VFR was significantly predictive of RMSSD, SDNN, and HF (p=0.002,-0.027), and MMVFR was significantly predictive of RMSSD and SDNN (p=0.020,-0.023).
Men in the lowest VFR category had the highest HRV. VFR was more strongly associated with HRV than body fat percentage and MMVR. Time domain parameters were more sensitive to VAT than frequency domain parameters. HRV parameters could be the primary parameters of interest in tracking cardiac-autonomic status in response to interventions targeting VAT reduction.
内脏脂肪组织（VAT）可能是与身体成分相关的自主神经损伤的一个特定的可改变的贡献因素。
比较按内脏脂肪分级（VFR）分层的组之间的心率变异性（HRV），并比较 HRV 与身体成分指标之间的关联。
对 99 名健康男性（年龄 37.8±13.4 岁，BMI=26.9±4.6kg/m2）进行了一项横断面研究。从 5 分钟的心电图记录中得出 HRV。使用四极生物电阻抗分析来估计身体成分（体脂百分比、VFR 和肌肉质量与内脏脂肪比[MMVFR]）。根据 VFR 将参与者分为三组：G1（VFR=1-8）；G2（VFR=9-12）；和 G3（VFR>12）。对组间进行年龄调整比较。使用多元线性回归量化独立关联。p<0.05 为有统计学意义。
G1 与 G2 和 G3 相比，均方根差（RMSSD）和正常 RR 间期标准差（SDNN）较高（p<0.05）。G1 的低频功率（LF）高于 G2（p<0.05）。VFR 和 MMVFR 与 SDNN、RMSSD、LF 和 HF 呈负相关（p<0.05）。在调整年龄、BMI、收缩压和舒张压后，VFR 与 RMSSD、SDNN 和 HF 显著相关（p=0.002，-0.027），MMVFR 与 RMSSD 和 SDNN 显著相关（p=0.020，-0.023）。
VFR 最低组的男性 HRV 最高。VFR 与 HRV 的相关性强于体脂百分比和 MMVR。时域参数比频域参数更能敏感地反映 VAT。HRV 参数可能是跟踪心脏自主神经状态的主要关注参数，以响应针对 VAT 减少的干预措施。
