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使用超声生物显微镜对艾哈迈德的结膜下皮瓣褥式缝合深层巩膜切除术进行评估。

Ahmed's sub-flap mattress suture deep sclerectomy assessment with Ultrasound Biomicroscopy.

作者信息

Habib Mina Maged, Hilmy Gihan Mohamed, AbdelRahman Ahmed Mostafa, Kotb Mohamed Sabry

机构信息

Ophthalmology department, Kasr Alainy, Faculty of Medicine, Cairo University, 3 Montaser Housing, Elaharam, Cairo, Giza, Egypt.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2025 Mar;263(3):797-806. doi: 10.1007/s00417-024-06598-4. Epub 2024 Oct 17.

Abstract

PURPOSE

To assess the efficacy of adding Ahmed's sub-flap mattress suture to deep sclerectomy (DS).

METHODS

Forty eyes with open angle glaucoma were assigned randomly into two groups: Group A: underwent DS with Ahmed's sub-flap mattress suture. Group B: underwent conventional DS. Patients were followed up closely for 6 months with serial IOP measurements and ultrasound biomicroscopy (UBM) was used to assess the surgical site functionally and anatomically at the first and sixth month.

RESULTS

Adding Ahmed's sub-flap mattress suture improved the IOP lowering effect of DS significantly from 43% in group B to 53% in group A at 6-month (p = 0.027). IOP in group A was at 1 week, 1 month and 6-month visits (7.9 ± 1.3, 11.7 ± 2.2 and 13.3 ± 1.9 mmHg respectively) compared to group B (10.1 ± 4.6, 14.1 ± 5.2 and 16.8 ± 4.1 mmHg respectively) (p = 0.025, 0.041 and 0.001 respectively). UBM parameters were significantly larger in group A at 1 and 6 months. Strong statistically significant negative correlations were established between IOP and all the UBM parameters apart from intrascleral lake height at the first and sixth month (p < 0.01 in all of them). Finally, significant correlations were found between IOP at 6 months and whole bleb anteroposterior length and height at 1 month (p = 0.001).

CONCLUSION

Adding Ahmed's sub-flap mattress suture to routine DS is an effective economical addition that will enhance the IOP lowering effect of DS. Also, assessment of the bleb by UBM is useful in predicting the success of deep sclerectomy surgery.

摘要

目的

评估在深层巩膜切除术(DS)中添加艾哈迈德瓣下褥式缝合的疗效。

方法

将40只开角型青光眼患眼随机分为两组:A组:接受DS并加用艾哈迈德瓣下褥式缝合。B组:接受传统DS。对患者进行为期6个月的密切随访,连续测量眼压,并在第1个月和第6个月使用超声生物显微镜(UBM)从功能和解剖学角度评估手术部位。

结果

添加艾哈迈德瓣下褥式缝合显著提高了DS降低眼压的效果,6个月时B组为43%,A组为53%(p = 0.027)。A组在第1周、1个月和6个月随访时的眼压分别为(7.9 ± 1.3、11.7 ± 2.2和13.3 ± 1.9 mmHg),而B组分别为(10.1 ± 4.6、14.1 ± 5.2和16.8 ± 4.1 mmHg)(p分别为0.025、0.041和0.001)。A组在第1个月和第6个月时的UBM参数明显更大。在第1个月和第6个月时,除巩膜内湖高度外,眼压与所有UBM参数之间均建立了强统计学意义的负相关(所有p均 < 0.01)。最后,发现6个月时的眼压与1个月时整个滤过泡的前后径和高度之间存在显著相关性(p = 0.001)。

结论

在常规DS中添加艾哈迈德瓣下褥式缝合是一种有效且经济的方法,可增强DS降低眼压的效果。此外,通过UBM评估滤过泡有助于预测深层巩膜切除术的成功与否。

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