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在初级保健环境中诊断和管理强迫症。

Diagnosis and Management of Obsessive-Compulsive Disorder in the Primary Care Setting.

机构信息

Tristar Nashville (Tenn.) Family Medicine Residency Program.

出版信息

Am Fam Physician. 2024 Oct;110(4):385-392.

Abstract

Obsessive-compulsive disorder is a common neuropsychiatric disorder that is often underdiagnosed or misdiagnosed. It is characterized by obsessions, which are intrusive and include unwanted thoughts, images, or urges that cause marked anxiety or distress. Obsessions also drive patients to engage in repetitive actions or thoughts, known as compulsions. The condition has a high prevalence of comorbid disorders and can be associated with functional impairment. Early recognition and treatment can lead to improved outcomes, and complete remission is possible. Validated tools, such as the Yale-Brown Obsessive-Compulsive Scale, are effective in diagnosing and monitoring obsessive-compulsive disorder and determining the severity of the condition. Severity varies among cases, and proper diagnosis and education about this condition are important for determining a treatment plan, which can include psychotherapy, pharmacotherapy, or both. Exposure and response prevention is the most effective form of psychotherapy, and selective serotonin reuptake inhibitors are the most effective pharmacotherapy. If monotherapy is not effective, psychotherapy and pharmacotherapy can be combined. Treatment of obsessive-compulsive disorder is typically recommended for at least 12 months for maintenance and prevention of relapse. In patients requiring augmentation, higher-risk or novel adjunctive treatments or investigational therapies should be managed by an experienced multidisciplinary team.

摘要

强迫症是一种常见的神经精神障碍,常常被漏诊或误诊。其特征为强迫观念,即反复出现、无法控制的、包括不必要的想法、图像或冲动,引起明显的焦虑或痛苦。强迫观念还驱使患者进行重复的动作或思维,即强迫行为。这种疾病的共病率很高,可能与功能损害有关。早期识别和治疗可以改善预后,完全缓解是可能的。经过验证的工具,如耶鲁-布朗强迫量表,可有效诊断和监测强迫症,并确定病情的严重程度。病情的严重程度因人而异,因此,正确诊断和了解这种疾病对于确定治疗计划非常重要,治疗计划可能包括心理治疗、药物治疗或两者结合。暴露和反应预防是最有效的心理治疗形式,选择性 5-羟色胺再摄取抑制剂是最有效的药物治疗。如果单一疗法无效,可以将心理治疗和药物治疗相结合。强迫症的治疗通常建议至少维持 12 个月,以预防复发。对于需要增效治疗的患者,应由经验丰富的多学科团队管理高风险或新型辅助治疗或试验性治疗。

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