Almroth Melody, Hemmingsson Tomas, Falkstedt Daniel, Carlsson Emma, Kjellberg Katarina, Thern Emelie
Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Department of Public Health Sciences, Stockholm University, Stockholm, Sweden.
Eur J Public Health. 2024 Dec 1;34(6):1134-1139. doi: 10.1093/eurpub/ckae158.
This study aims to investigate the relationship between education and alcohol-related morbidity and the role that low job control and heavy physical workload play in explaining these associations among men and women in Sweden. This register-based cohort study (SWIP cohort) includes over three million individuals registered in Sweden in 2005. Job control and physical workload were measured using a job exposure matrix linked to the index person based on their registered occupation at baseline. Alcohol-related morbidity was measured through diagnoses in the national patient registers between 2006 and 2020. Cox proportional hazards regression models were built to estimate associations between education and alcohol-related morbidity. Reductions in hazard ratios (HRs) were calculated after adjusting for job control, physical workload, and other covariates. Models were also stratified by sex. Lower levels of education predicted a higher risk of alcohol-related morbidity (HR: 2.55 95% confidence interval: 2.49-2.62 for the lowest educated compared to the highest). Low job control and heavy physical workload both played roles in explaining educational differences in alcohol-related morbidity even after accounting for sociodemographic and health factors (15.1% attenuation for job control and 18.3% for physical workload among the lowest educated). Physical workload explained a larger proportion of the associations among men compared to women. Lower levels of education were associated with an increased risk of alcohol-related morbidity and working conditions partly explained these associations beyond what was explained by sociodemographic and health factors. Improving working conditions could therefore prevent some cases of alcohol-related morbidity.
本研究旨在调查教育与酒精相关疾病之间的关系,以及低工作控制和繁重体力劳动负荷在解释瑞典男性和女性之间这些关联中所起的作用。这项基于登记的队列研究(SWIP队列)包括2005年在瑞典登记的300多万人。工作控制和体力劳动负荷是根据基线时登记的职业,使用与索引人物相关的工作暴露矩阵来衡量的。酒精相关疾病是通过2006年至2020年期间国家患者登记中的诊断来衡量的。构建Cox比例风险回归模型以估计教育与酒精相关疾病之间的关联。在调整工作控制、体力劳动负荷和其他协变量后计算风险比(HR)降低情况。模型也按性别分层。较低的教育水平预示着酒精相关疾病的风险更高(与最高学历相比,最低学历的HR:2.55,95%置信区间:2.49 - 2.62)。即使在考虑了社会人口统计学和健康因素之后,低工作控制和繁重体力劳动负荷在解释酒精相关疾病的教育差异方面都发挥了作用(在最低学历人群中,工作控制导致的衰减为15.1%,体力劳动负荷导致的衰减为18.3%)。与女性相比,体力劳动负荷在男性之间的关联中解释的比例更大。较低的教育水平与酒精相关疾病风险增加相关,工作条件在一定程度上解释了这些关联,超出了社会人口统计学和健康因素所能解释的范围。因此,改善工作条件可以预防一些酒精相关疾病的发生。