• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

小儿患者的颅面部原发性高分化低度中央型骨肉瘤：一例报告

Craniofacial primary well-differentiated low-grade central osteosarcoma in a paediatric patient: a case report.

作者信息

Cázares-Vázquez Pablo Horacio, Silva-Suárez Richael Antonio, Ortiz-Álvarez Franco Andrés, Gaytán-Fernández Guillermo Joaquín Guillermo, Flores-Vargas Gilberto, Padilla-Raygoza Nicolás

机构信息

Department of General Surgery, Hospital General León, Institute of Public Health from Guanajuato State, León CP 37672, Mexico.

Department of Maxillofacial Surgery, Hospital General León, Institute of Public Health from Guanajuato State, León CP 37672, Mexico.

出版信息

Ecancermedicalscience. 2024 Aug 29;18:1752. doi: 10.3332/ecancer.2024.1752. eCollection 2024.

DOI:10.3332/ecancer.2024.1752
PMID:39421186
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11484673/
Abstract

Osteosarcoma is a primary malignant tumour that accounts for less than 1% of cancers diagnosed annually in the United States and 3% of all cancers in paediatric patients. Surgical treatment and adjuvant chemotherapy are essential to improve short- and long-term survival. In this report, we present the case of an 11-month-old female patient referred to the first level of care for a suspected tumour in the left orbit, who underwent biopsy and tumour resection surgery by the maxillofacial surgery service and underwent adjuvant chemotherapy in a specialised centre. Timely detection of cancer in the paediatric population, as well as multidisciplinary management and close surveillance, improves the survival and quality of life of patients.

摘要

骨肉瘤是一种原发性恶性肿瘤，在美国每年诊断出的癌症中占比不到1%，在儿科患者所有癌症中占3%。手术治疗和辅助化疗对于提高短期和长期生存率至关重要。在本报告中，我们介绍了一名11个月大的女性患者的病例，该患者因疑似左眼眶肿瘤被转诊至一级护理机构，接受了颌面外科服务的活检和肿瘤切除手术，并在一家专业中心接受了辅助化疗。儿科人群中癌症的及时检测以及多学科管理和密切监测可提高患者的生存率和生活质量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/c17626f394d4/can-18-1752fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/bc0210634064/can-18-1752fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/eb7689b2a5f5/can-18-1752fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/c5cdd1c8f8d7/can-18-1752fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/1922761ef37e/can-18-1752fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/49973f48f4e6/can-18-1752fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/61f3dfd790dd/can-18-1752fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/c17626f394d4/can-18-1752fig7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/bc0210634064/can-18-1752fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/eb7689b2a5f5/can-18-1752fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/c5cdd1c8f8d7/can-18-1752fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/1922761ef37e/can-18-1752fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/49973f48f4e6/can-18-1752fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/61f3dfd790dd/can-18-1752fig6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76d9/11484673/c17626f394d4/can-18-1752fig7.jpg

相似文献

1
Craniofacial primary well-differentiated low-grade central osteosarcoma in a paediatric patient: a case report.小儿患者的颅面部原发性高分化低度中央型骨肉瘤：一例报告
Ecancermedicalscience. 2024 Aug 29;18:1752. doi: 10.3332/ecancer.2024.1752. eCollection 2024.
2
Low-Grade Surface Osteosarcoma of the Temporal Bone in Paediatric Patients: A Case Report and Literature Review.儿童颞骨低度表面骨肉瘤：一例报告及文献复习
Clin Med Insights Pediatr. 2019 Jun 26;13:1179556519855381. doi: 10.1177/1179556519855381. eCollection 2019.
3
Spinal osteosarcoma in the paediatric age group: case series and literature review.小儿年龄组的脊柱骨肉瘤：病例系列及文献综述
Rev Esp Cir Ortop Traumatol (Engl Ed). 2019 Mar-Apr;63(2):122-131. doi: 10.1016/j.recot.2018.09.001. Epub 2019 Feb 8.
4
Is Surgical Resection of the Primary Site Associated with an Improved Overall Survival for Patients with Primary Malignant Bone Tumors Who Have Metastatic Disease at Presentation?对于初诊时即发生转移的原发性骨恶性肿瘤患者，外科切除原发灶是否能提高总生存率？
Clin Orthop Relat Res. 2020 Oct;478(10):2284-2295. doi: 10.1097/CORR.0000000000001361.
5
3-month versus 6-month adjuvant chemotherapy for patients with high-risk stage II and III colorectal cancer: 3-year follow-up of the SCOT non-inferiority RCT.高危 II 期和 III 期结直肠癌患者的 3 个月与 6 个月辅助化疗：SCOT 非劣效 RCT 的 3 年随访。
Health Technol Assess. 2019 Dec;23(64):1-88. doi: 10.3310/hta23640.
6
Primary osteosarcoma of the skull in teenager.青少年颅骨原发性骨肉瘤
BMJ Case Rep. 2019 Sep 16;12(9):e229585. doi: 10.1136/bcr-2019-229585.
7
Maxillofacial osteosarcoma successfully treated with surgery and adjuvant chemotherapy in a child.一名儿童颌面部骨肉瘤经手术及辅助化疗成功治愈。
Bratisl Lek Listy. 2012;113(11):661-3. doi: 10.4149/bll_2012_149.
8
Neoadjuvant Chemotherapy Followed by Delayed Surgery: Is it Necessary for All Patients With Nonmetastatic High-Grade Pelvic Osteosarcoma?新辅助化疗后延迟手术：所有非转移性高级骨盆骨肉瘤患者都需要吗？
Clin Orthop Relat Res. 2018 Nov;476(11):2177-2186. doi: 10.1097/CORR.0000000000000387.
9
Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial.新诊断的高级别骨肉瘤术前化疗反应不佳患者中MAPIE与MAP的比较（EURAMOS-1）：一项开放标签、国际、随机对照试验
Lancet Oncol. 2016 Oct;17(10):1396-1408. doi: 10.1016/S1470-2045(16)30214-5. Epub 2016 Aug 25.
10
Zoledronate in combination with chemotherapy and surgery to treat osteosarcoma (OS2006): a randomised, multicentre, open-label, phase 3 trial.唑来膦酸联合化疗和手术治疗骨肉瘤（OS2006）：一项随机、多中心、开放标签、3 期临床试验。
Lancet Oncol. 2016 Aug;17(8):1070-1080. doi: 10.1016/S1470-2045(16)30096-1. Epub 2016 Jun 17.

本文引用的文献

1
Nationwide incidence of sarcomas and connective tissue tumors of intermediate malignancy over four years using an expert pathology review network.利用专家病理审查网络，四年间全国范围内的中间恶性肉瘤和结缔组织肿瘤的发病率。
PLoS One. 2021 Feb 25;16(2):e0246958. doi: 10.1371/journal.pone.0246958. eCollection 2021.
2
Updates from the 2020 World Health Organization Classification of Soft Tissue and Bone Tumours.2020 年世界卫生组织软组织和骨肿瘤分类更新。
Histopathology. 2021 Apr;78(5):644-657. doi: 10.1111/his.14265. Epub 2021 Jan 12.
3
Frequency of Pathogenic Germline Variants in Cancer-Susceptibility Genes in Patients With Osteosarcoma.
骨肉瘤患者中癌症易感性基因种系致病性变异的频率。
JAMA Oncol. 2020 May 1;6(5):724-734. doi: 10.1001/jamaoncol.2020.0197.
4
Effectiveness of F-FDG PET/CT in the diagnosis and staging of osteosarcoma: a meta-analysis of 26 studies.F-FDG PET/CT 对骨肉瘤诊断和分期的有效性：26 项研究的荟萃分析。
BMC Cancer. 2019 Apr 5;19(1):323. doi: 10.1186/s12885-019-5488-5.
5
Estimating the total incidence of global childhood cancer: a simulation-based analysis.估算全球儿童癌症总发病率：基于模拟的分析。
Lancet Oncol. 2019 Apr;20(4):483-493. doi: 10.1016/S1470-2045(18)30909-4. Epub 2019 Feb 26.
6
Primary Osteosarcoma in the Elderly Revisited: Current Concepts in Diagnosis and Treatment.老年人原发性骨肉瘤再探：诊断与治疗的当前概念。
Curr Oncol Rep. 2018 Feb 28;20(2):13. doi: 10.1007/s11912-018-0658-1.
7
Comparison of the AJCC, MSTS, and Modified Spanier Systems for Clinical and Pathologic Staging of Osteosarcoma.AJCC、MSTS 和改良 Spanier 系统在骨肉瘤临床和病理分期中的比较。
Am J Surg Pathol. 2017 Mar;41(3):405-413. doi: 10.1097/PAS.0000000000000774.
8
Low-grade central osteosarcoma: a difficult condition to diagnose.低级别中央型骨肉瘤：一种难以诊断的病症。
Sarcoma. 2012;2012:764796. doi: 10.1155/2012/764796. Epub 2012 Jul 16.
9
Chemotherapeutic adjuvant treatment for osteosarcoma: where do we stand?骨肉瘤的化学辅助治疗：我们处于什么位置？
Eur J Cancer. 2011 Nov;47(16):2431-45. doi: 10.1016/j.ejca.2011.05.030. Epub 2011 Jun 22.
10
The epidemiology of osteosarcoma.骨肉瘤的流行病学
Cancer Treat Res. 2009;152:3-13. doi: 10.1007/978-1-4419-0284-9_1.