高血糖患者的登革热:一个新出现的公共卫生问题,需要关注有效的管理策略。

Dengue fever in hyperglycemic patients: an emerging public health concern demanding eyes on the effective management strategies.

作者信息

Shawon Shandipon Roy, Hamid Mohammad Khaled Iqbal, Ahmed Hossain, Khan Sakif Ahamed, Dewan Syed Masudur Rahman

机构信息

Department of Pharmacy, School of Medicine University of Asia Pacific Dhaka Bangladesh.

Department of Pharmacy, School of Life Sciences United International University Dhaka Bangladesh.

出版信息

Health Sci Rep. 2024 Oct 16;7(10):e70144. doi: 10.1002/hsr2.70144. eCollection 2024 Oct.

Abstract

BACKGROUND AND AIMS

Hyperglycemia, also known as diabetes, is a metabolic disorder characterized by elevated levels of glucose in the bloodstream. It can lead to the prolonged dysfunction, injury, and deterioration of several organs. In addition, dengue is a viral illness transmitted by mosquitoes that has reached epidemic proportions worldwide. In this article, we focused on the severity of comorbidities, difficulties in managing them, and preventive measures meant to lessen the risks associated with comorbidities in diabetic patients with dengue infection.

METHODS

We explored a number of databases, including PubMed, Scopus, Embase, Web of Science, Google Scholar, and the Cochrane Library, for this review article using various related keywords.

RESULTS

The findings of this review article indicate that elderly dengue patients with diabetes should be admitted to the hospital for close observation and early management using fluid therapy. An observed association exists between dengue hemorrhagic fever (DHF) and diabetes, indicating a possible consequence in this specific group. Additionally, patients with diabetes who contract dengue show elevated levels of inflammatory markers. Diabetes mellitus deteriorates the immune system, which exacerbates the progression of dengue fever. Cutting-edge technology and scientific research may assist in addressing the challenges that diabetes and dengue viruses pose in low- and middle-income countries. Implementing innovative diabetic care management is essential to ensuring consistency of care, improving a healthy lifestyle, and lowering patient risk factors and comorbidities.

CONCLUSION

Dengue fever has spread to epidemic levels throughout the world. Inflammatory markers increase and the prevalence of DHF is greater in diabetes individuals with dengue infection. Given the continued growth of dengue in Asian nations, it is imperative that we concentrate our efforts and resources on providing more precise and effective treatment for this emerging issue.

摘要

背景与目的

高血糖,又称糖尿病,是一种代谢紊乱疾病,其特征为血液中葡萄糖水平升高。它可导致多个器官长期功能障碍、损伤及恶化。此外,登革热是一种由蚊子传播的病毒性疾病,已在全球范围内达到流行程度。在本文中,我们聚焦于糖尿病合并登革热感染患者的合并症严重程度、管理困难以及旨在降低与合并症相关风险的预防措施。

方法

我们使用各种相关关键词,在多个数据库中进行检索,包括PubMed、Scopus、Embase、科学网、谷歌学术和考克兰图书馆,以撰写本综述文章。

结果

本综述文章的研究结果表明,患有糖尿病的老年登革热患者应住院接受密切观察,并采用液体疗法进行早期管理。观察到登革出血热(DHF)与糖尿病之间存在关联,这表明在这一特定群体中可能会产生某种后果。此外,感染登革热的糖尿病患者炎症标志物水平升高。糖尿病会使免疫系统恶化,从而加剧登革热的病情发展。前沿技术和科学研究可能有助于应对糖尿病和登革热病毒在低收入和中等收入国家带来的挑战。实施创新的糖尿病护理管理对于确保护理的一致性、改善健康生活方式以及降低患者风险因素和合并症至关重要。

结论

登革热已在全球蔓延至流行程度。登革热感染的糖尿病患者炎症标志物增加,登革出血热的患病率更高。鉴于登革热在亚洲国家持续增多,我们必须集中精力和资源,为这一新兴问题提供更精确有效的治疗。

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