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登革出血热:日益严重的全球威胁。

Dengue hemorrhagic fever: a growing global menace.

机构信息

Department of Zoology, The Government Sadiq College Women University, Bahawalpur 63100, Pakistan E-mail:

Department of Zoology, The Government Sadiq College Women University, Bahawalpur 63100, Pakistan.

出版信息

J Water Health. 2023 Nov;21(11):1632-1650. doi: 10.2166/wh.2023.114.

Abstract

Dengue virus is an arthropod-borne virus, transmitted by Aedes aegypti among humans. In this review, we discussed the epidemiology of dengue hemorrhagic fever (DHF) as well as the disease's natural history, cycles of transmission, clinical diagnosis, aetiology, prevention, therapy, and management. A systematic literature search was done by databases such as PubMed and Google Scholar using search terms, 'dengue fever', 'symptoms and causes of dengue fever', 'dengue virus transmission', and 'strategies to control dengue'. We reviewed relevant literature to identify hazards related to DHF and the most recent recommendations for its management and prevention. Clinical signs and symptoms of dengue infection range from mild dengue fever (DF) to potentially lethal conditions like DHF or dengue shock syndrome (DSS). Acute-onset high fever, muscle and joint pain, myalgia, a rash on the skin, hemorrhagic episodes, and circulatory shock are among the most common symptoms. An early diagnosis is vital to lower mortality. As dengue virus infections are self-limiting, but in tropical and subtropical areas, dengue infection has become a public health concern. Hence, developing and executing long-term control policies that can reduce the global burden of DHF is a major issue for public health specialists everywhere.

摘要

登革热病毒是一种虫媒病毒,通过埃及伊蚊在人与人之间传播。在这篇综述中,我们讨论了登革出血热(DHF)的流行病学,以及该病的自然史、传播周期、临床诊断、病因学、预防、治疗和管理。通过使用“登革热”、“登革热的症状和病因”、“登革热病毒传播”和“登革热控制策略”等搜索词,在 PubMed 和 Google Scholar 等数据库中进行了系统的文献检索。我们回顾了相关文献,以确定与 DHF 相关的危害以及其最新的管理和预防建议。登革热感染的临床症状和体征从轻度登革热(DF)到潜在致命的情况,如 DHF 或登革热休克综合征(DSS)不等。急性发作的高热、肌肉和关节疼痛、肌痛、皮肤出疹、出血发作和循环性休克是最常见的症状。早期诊断对于降低死亡率至关重要。由于登革热病毒感染是自限性的,但在热带和亚热带地区,登革热感染已成为公共卫生关注的问题。因此,制定和执行可以减轻全球 DHF 负担的长期控制政策是所有公共卫生专家的主要问题。

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