慢性淋巴细胞白血病相关肾病综合征的综述。
A review of nephrotic syndrome associated with chronic lymphocytic leukemia.
作者信息
Seney F D, Federgreen W R, Stein H, Kashgarian M
出版信息
Arch Intern Med. 1986 Jan;146(1):137-41.
PMID:3942445
Abstract
Four patients had the nephrotic syndrome and chronic lymphocytic leukemia (CLL), which may be pathogenetically related. Membranoproliferative glomerulonephritis appears to be the most common glomerular lesion in patients with CLL. Available evidence suggests that nephrotic syndrome associated with CLL is often related to immune-complex disease. It is also possible that disorders of immunoglobulin production and cellular immunity contribute to renal disease in patients with CLL.
摘要
4例患者患有肾病综合征和慢性淋巴细胞白血病（CLL），二者在发病机制上可能相关。膜增生性肾小球肾炎似乎是CLL患者中最常见的肾小球病变。现有证据表明，与CLL相关的肾病综合征通常与免疫复合物疾病有关。免疫球蛋白产生和细胞免疫紊乱也可能导致CLL患者出现肾脏疾病。
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