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Cefiderocol is Not Sequestered in an Ex Vivo Extracorporeal Membrane Oxygenation (ECMO) Circuit.头孢地尔在体外膜肺氧合（ECMO）回路中不被隔离。
Eur J Drug Metab Pharmacokinet. 2023 Jul;48(4):437-441. doi: 10.1007/s13318-023-00840-w. Epub 2023 Jun 23.
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Pharmacokinetics of cefiderocol during extracorporeal membrane oxygenation: A case report.体外膜肺氧合期间头孢地尔的药代动力学：病例报告。
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Pharmacokinetics/pharmacodynamics of cefiderocol administered by continuous infusion in a case series of critically ill patients with carbapenem-resistant Acinetobacter baumannii infections undergoing continuous venovenous haemodiafiltration (CVVHDF).头孢地尔在接受连续静脉-静脉血液透析滤过（CVVHDF）的重症耐碳青霉烯鲍曼不动杆菌感染患者病例系列中连续输注时的药代动力学/药效学。
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Continuous infusion of cefiderocol in a critically ill patient with continuous venovenous haemofiltration.连续静脉-静脉血液滤过治疗危重症患者时持续输注头孢地尔。
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Pharmacokinetics of Imipenem in Critically Ill Patients with Life-threatening Severe Infections During Support with Extracorporeal Membrane Oxygenation.严重危及生命感染的体外膜肺氧合支持下的危重病患者中亚胺培南的药代动力学。
Clin Drug Investig. 2019 Aug;39(8):787-798. doi: 10.1007/s40261-019-00796-3.

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Towards a holistic approach to pulmonary infections. Insights from the Sixth Annual Meeting of Spanish Experts 2024.迈向肺部感染的整体治疗方法。来自2024年西班牙专家第六届年会的见解。
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本文引用的文献

1
No Sequestration of Commonly Used Anti-Infectives in the Extracorporeal Membrane Oxygenation (ECMO) Circuit-An Ex Vivo Study.体外膜肺氧合（ECMO）回路中常用抗感染药物无截留——一项体外研究
Antibiotics (Basel). 2024 Apr 19;13(4):373. doi: 10.3390/antibiotics13040373.
2
Nosocomial Infections in Adults Receiving Extracorporeal Membrane Oxygenation: A Review for Infectious Diseases Clinicians.成人体外膜肺氧合患者的医院感染：传染病临床医生的综述。
Clin Infect Dis. 2024 Aug 16;79(2):412-419. doi: 10.1093/cid/ciae120.
3
Cefiderocol is Not Sequestered in an Ex Vivo Extracorporeal Membrane Oxygenation (ECMO) Circuit.头孢地尔在体外膜肺氧合（ECMO）回路中不被隔离。
Eur J Drug Metab Pharmacokinet. 2023 Jul;48(4):437-441. doi: 10.1007/s13318-023-00840-w. Epub 2023 Jun 23.
4
Pharmacokinetics/pharmacodynamics of cefiderocol administered by continuous infusion in a case series of critically ill patients with carbapenem-resistant Acinetobacter baumannii infections undergoing continuous venovenous haemodiafiltration (CVVHDF).头孢地尔在接受连续静脉-静脉血液透析滤过（CVVHDF）的重症耐碳青霉烯鲍曼不动杆菌感染患者病例系列中连续输注时的药代动力学/药效学。
Int J Antimicrob Agents. 2023 Aug;62(2):106852. doi: 10.1016/j.ijantimicag.2023.106852. Epub 2023 May 14.
5
Pharmacokinetics of cefiderocol during extracorporeal membrane oxygenation: A case report.体外膜肺氧合期间头孢地尔的药代动力学：病例报告。
Perfusion. 2023 May;38(1_suppl):40-43. doi: 10.1177/02676591231160462. Epub 2023 Feb 28.
6
Pharmacokinetics, Pharmacodynamics, and Dosing Considerations of Novel β-Lactams and β-Lactam/β-Lactamase Inhibitors in Critically Ill Adult Patients: Focus on Obesity, Augmented Renal Clearance, Renal Replacement Therapies, and Extracorporeal Membrane Oxygenation.新型β-内酰胺类药物和β-内酰胺/β-内酰胺酶抑制剂在危重症成年患者中的药代动力学、药效学及给药考量：聚焦肥胖、肾脏清除率增加、肾脏替代治疗及体外膜肺氧合
J Clin Med. 2022 Nov 22;11(23):6898. doi: 10.3390/jcm11236898.
7
Antimicrobial Exposures in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation.接受体外膜肺氧合治疗的重症患者的抗菌药物暴露情况。
Am J Respir Crit Care Med. 2023 Mar 15;207(6):704-720. doi: 10.1164/rccm.202207-1393OC.
8
A descriptive case series of pharmacokinetic/pharmacodynamic target attainment and microbiological outcome in critically ill patients with documented severe extensively drug-resistant Acinetobacter baumannii bloodstream infection and/or ventilator-associated pneumonia treated with cefiderocol.头孢地尔治疗确诊为严重广泛耐药鲍曼不动杆菌血流感染和/或呼吸机相关性肺炎的危重症患者的药代动力学/药效学目标达标情况和微生物学结局的描述性病例系列研究。
J Glob Antimicrob Resist. 2021 Dec;27:294-298. doi: 10.1016/j.jgar.2021.10.014. Epub 2021 Oct 26.
9
Intrapulmonary pharmacokinetic profile of cefiderocol in mechanically ventilated patients with pneumonia.肺部药物动力学：机械通气肺炎患者头孢地尔的体内过程。
J Antimicrob Chemother. 2021 Oct 11;76(11):2902-2905. doi: 10.1093/jac/dkab280.
10
Cefiderocol Pharmacokinetics in a Patient Receiving Continuous Venovenous Hemodiafiltration.接受持续静脉-静脉血液透析滤过患者的头孢地尔药代动力学
Open Forum Infect Dis. 2021 May 25;8(7):ofab252. doi: 10.1093/ofid/ofab252. eCollection 2021 Jul.

Cefiderocol pharmacokinetics in critically ill patients undergoing ECMO support.

作者信息

Marín-Cerezuela María, Martín-Latorre Ruben, Frasquet Juan, Ruiz-Ramos Jesus, Garcia-Contreras Sandra, Gordón Mónica, Broch María Jesús, Castellanos-Ortega Álvaro, Ramirez Paula

机构信息

Pharmacy Department, Hospital Universitario y Politécnico la Fe, Valencia, Spain.

Critical Care Department, Hospital Universitario y Politécnico la Fe, Avd. Vicente Abril Martorell 106, 46006, Valencia, Spain.

出版信息

Crit Care. 2024 Oct 18;28(1):337. doi: 10.1186/s13054-024-05126-4.

DOI:10.1186/s13054-024-05126-4
PMID:39425201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11488226/
Abstract
摘要