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一名儿科患者的嗜麦芽窄食单胞菌坏死性扁桃体炎:一种伴有上呼吸道梗阻的罕见表现。

Stenotrophomonas Necrotizing Tonsilitis in a Pediatric Patient: A Rare Presentation With Upper Airway Obstruction.

作者信息

Oui Ting Jie, Goh Bee See, Lokman Farah Liana, Kew Thean Yean, Teo Rufinah

机构信息

Otorhinolaryngology - Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.

Radiology, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, MYS.

出版信息

Cureus. 2024 Sep 18;16(9):e69627. doi: 10.7759/cureus.69627. eCollection 2024 Sep.

DOI:10.7759/cureus.69627
PMID:39429278
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11488991/
Abstract

is notorious for its intrinsic resistance to many commonly used antibiotics, making it a particularly challenging pathogen to treat. It often causes severe opportunistic infections in immunocompromised and hospitalized patients. The potential for this infection to become fulminant with high mortality rates in both adults and children necessitates a multidisciplinary approach. Prompt initiation of appropriate antibiotic therapy can be lifesaving. In this case report, we present a rare instance involving an eight-month-old previously healthy infant diagnosed with necrotizing tonsillitis and a retropharyngeal abscess, which led to upper airway obstruction. Intraoperative tissue cultures identified this highly virulent gram-negative bacillus. The report details the medical and surgical management that resulted in the patient's complete recovery.

摘要

因其对许多常用抗生素具有内在抗性而臭名昭著,使其成为一种特别难以治疗的病原体。它经常在免疫功能低下和住院患者中引起严重的机会性感染。这种感染在成人和儿童中都有可能发展为暴发性感染并导致高死亡率,因此需要采取多学科方法。及时开始适当的抗生素治疗可能会挽救生命。在本病例报告中,我们呈现了一个罕见的病例,一名八个月大的此前健康的婴儿被诊断患有坏死性扁桃体炎和咽后脓肿,这导致了上呼吸道阻塞。术中组织培养鉴定出这种高毒力的革兰氏阴性杆菌。该报告详细介绍了导致患者完全康复的医疗和手术管理情况。

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本文引用的文献

1
Community-Acquired Stenotrophomonas Maltophilia Infection in a Child: A Case Report and Literature Review.儿童社区获得性嗜麦芽窄食单胞菌感染:一例报告及文献复习
Infect Drug Resist. 2022 Sep 19;15:5469-5474. doi: 10.2147/IDR.S376712. eCollection 2022.
2
Stenotrophomonas maltophilia as a Cause of Meningitis in an Infant.嗜麦芽窄食单胞菌作为一名婴儿脑膜炎的病因
Indian J Pediatr. 2021 Jul;88(7):726. doi: 10.1007/s12098-021-03800-x. Epub 2021 May 20.
3
Stenotrophomonas maltophilia bacteremia in children - A 10-year analysis.嗜麦芽寡养单胞菌菌血症患儿-10 年分析。
Arch Argent Pediatr. 2020 Jun;118(3):e317-e323. doi: 10.5546/aap.2020.eng.e317.
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Primary tonsillar tuberculosis: a forgotten clinical identity.原发性扁桃体结核:一个被遗忘的临床病种。
Iran J Microbiol. 2019 Dec;11(6):542-545.
5
A global priority list of the TOp TEn resistant Microorganisms (TOTEM) study at intensive care: a prioritization exercise based on multi-criteria decision analysis.重症监护领域耐多药十大微生物全球优先清单研究(TOTEM):基于多准则决策分析的优先排序研究。
Eur J Clin Microbiol Infect Dis. 2019 Feb;38(2):319-323. doi: 10.1007/s10096-018-3428-y. Epub 2018 Nov 13.
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Bacteriology and antibiotic sensitivity of tonsillar diseases in Chinese children.中国儿童扁桃体疾病的细菌学及抗生素敏感性
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Necrotizing herpes-simplex virus tonsillitis mimicking peritonsillar abscess.酷似扁桃体周脓肿的坏死性单纯疱疹病毒扁桃体炎
Infection. 2016 Apr;44(2):267-8. doi: 10.1007/s15010-015-0823-5. Epub 2015 Jul 21.
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Acute necrotizing herpetic tonsillitis: a report of two cases.急性坏死性疱疹性扁桃体炎:两例报告
Head Neck Pathol. 2015 Mar;9(1):119-22. doi: 10.1007/s12105-013-0516-2. Epub 2013 Dec 14.
9
Community-acquired Stenotrophomonas maltophilia infections: a systematic review.社区获得性嗜麦芽窄食单胞菌感染:一项系统评价
Eur J Clin Microbiol Infect Dis. 2009 Jul;28(7):719-30. doi: 10.1007/s10096-009-0709-5. Epub 2009 Feb 18.