Cook Michael J, Puri Basant K
Vis À Vis Symposiums, Bury St Edmunds, UK.
CAR, Cambridge, UK.
Int J Gen Med. 2024 Oct 14;17:4627-4631. doi: 10.2147/IJGM.S485759. eCollection 2024.
Human babesiosis is caused when erythrocytes are invaded by . Infection can occur from the bite of an infected tick, blood transfusion or congenitally. Issues related to the infecting species, symptomology and testing technology are discussed and the implications of accurate incidence and prevalence of the disease discussed. Human babesiosis is considered to be relatively rare in the UK. With a considerable number of non-specific symptoms and diagnostic testing limitations, it is probable that true positives are being missed. Based on co-infection data for and from Rhode Island and Connecticut, and on seropositivity data from northeastern France, the prevalence of babesiosis in those aged under 35 years, 35 to 44 years, 45 to 54 years and 55 years and over would be expected to be 0.6%, 1.8%, 2.8% and 3.5%, respectively. Based on the prevalence of infections in ticks and canines and a disease model previously published, it is estimated that the UK incidence of human babesiosis is likely to be approximately 18,500 cases per year.
人巴贝斯虫病是由 侵入红细胞时引起的。感染可通过受感染蜱虫叮咬、输血或先天性感染发生。文中讨论了与感染物种、症状学和检测技术相关的问题，并探讨了该疾病准确发病率和患病率的影响。人巴贝斯虫病在英国被认为相对罕见。由于有大量非特异性症状且诊断检测存在局限性，很可能会漏诊真正的阳性病例。根据罗德岛和康涅狄格州关于 和 的合并感染数据，以及法国东北部的 血清阳性数据，预计35岁以下、35至44岁、45至54岁以及55岁及以上人群中巴贝斯虫病的患病率分别为0.6%、1.8%、2.8%和3.5%。根据蜱虫和犬类感染的患病率以及先前发表的疾病模型，估计英国每年人巴贝斯虫病的发病率可能约为18,500例。
