Toader Corneliu, Radoi Mugurel Petrinel, Glavan Luca-Andrei, Covache-Busuioc Razvan-Adrian, Ilie Milena Monica, Popa Mihail, Dumitru Adrian
Department of Neurosurgery, Carol Davila University of Medicine and Pharmacy, Bucharest, ROU.
Department of Vascular Neurosurgery, National Institute of Neurology and Neurovascular Diseases, Bucharest, ROU.
Cureus. 2024 Oct 6;16(10):e70950. doi: 10.7759/cureus.70950. eCollection 2024 Oct.
This case report presents an exceedingly rare instance of skull base chondromyxoid fibroma (CMF) managed surgically. Chondromyxoid fibromas are very rare tumors (<1% of benign bone tumors), the occurrence in the skull area being even more rare. The location of tumors at the skull base makes their surgical resection extremely challenging, usually resulting in subtotal resection (STR). One aspect that makes this case stand out is its unique clinical presentation, particularly the presence of epileptic seizures. Patients suffering from skull base CMFs must receive regular follow-up exams in order to track disease progress, maintain quality of life, and prevent further complications.
本病例报告展示了一例极为罕见的经手术治疗的颅底软骨黏液样纤维瘤(CMF)。软骨黏液样纤维瘤是非常罕见的肿瘤(占良性骨肿瘤的比例不到1%),在颅骨区域发生的情况更为罕见。肿瘤位于颅底使得其手术切除极具挑战性,通常导致次全切除(STR)。使该病例脱颖而出的一个方面是其独特的临床表现,尤其是癫痫发作的存在。患有颅底CMF的患者必须接受定期随访检查,以便跟踪疾病进展、维持生活质量并预防进一步的并发症。