Huang Heng-Chiao, Cho Wan-Hua, Fang Po-Chiung, Lin Pei-Wen, Chen Yi-Hao, Huang Hsiu-Mei
Department of Ophthalmology, Chang Gung Memorial Hospital, Chiayi 613, Taiwan, China.
Department of Ophthalmology, Chi-Mei Medical Center, Tainan 710, Taiwan, China.
Int J Ophthalmol. 2024 Oct 18;17(10):1850-1856. doi: 10.18240/ijo.2024.10.11. eCollection 2024.
To evaluate the visual outcomes of standard amblyopic treatment add-on training perceptual learning in refractive amblyopic children and to identify the risk factors for treatment failure.
Retrospective charts were reviewed in children with refractive amblyopia who received standard treatment and add-on Cambridge Visual Stimulator (CAM) training. The add-on CAM group that was enrolled had worn full-corrected glasses for at least 2mo before training. A control group received only the standard treatment. Treatment success was defined as best-corrected visual acuity (BCVA) ≥20/25. The age, sex, initial BCVA, refractive errors, sessions and duration of training, and final BCVA were recorded.
A total of 209 children (129 children in add-on CAM group and 80 children in control group) were enrolled. Seventy-six percent of unilateral and 87% of bilateral amblyopic children achieved treatment success. In children with unilateral or bilateral moderate amblyopia, the duration to reach BCVA ≥20/25 was significantly shorter in add-on CAM group than in control group. Poor initial BCVA (<0.001) and high astigmatism (=0.007) were risk factors for treatment failure after add-on CAM training. Age, sex, and types of refractive error were not associated with treatment success.
Add-on CAM training is an effective strategy for visual improvement and can shorten the treatment course when the effect of standard treatment is limited in amblyopic children.
评估在屈光性弱视儿童中标准弱视治疗附加剑桥视觉刺激仪（CAM）训练的视觉效果，并确定治疗失败的危险因素。
回顾性分析接受标准治疗及附加CAM训练的屈光性弱视儿童的病历。纳入的附加CAM训练组在训练前已佩戴全矫眼镜至少2个月。对照组仅接受标准治疗。治疗成功定义为最佳矫正视力（BCVA）≥20/25。记录年龄、性别、初始BCVA、屈光不正、训练次数和时长以及最终BCVA。
共纳入209名儿童（附加CAM训练组129名，对照组80名）。76%的单眼弱视儿童和87%的双眼弱视儿童治疗成功。在单眼或双眼中度弱视儿童中，附加CAM训练组达到BCVA≥20/25的时间明显短于对照组。初始BCVA差（<0.001）和散光度数高（=0.007）是附加CAM训练后治疗失败的危险因素。年龄、性别和屈光不正类型与治疗成功无关。
在弱视儿童中，当标准治疗效果有限时，附加CAM训练是改善视力的有效策略，且可缩短治疗疗程。
