一种在理论和实践上更为有效的室性心动过速中断方法：自适应自动递减超速起搏。

A theoretically and practically more effective method for interruption of ventricular tachycardia: self-adapting autodecremental overdrive pacing.

作者信息

Charos G S, Haffajee C I, Gold R L, Bishop R L, Berkovits B V, Alpert J S

出版信息

Circulation. 1986 Feb;73(2):309-15. doi: 10.1161/01.cir.73.2.309.

DOI:10.1161/01.cir.73.2.309

Abstract

The efficacy and safety of a new antitachycardia pacing technique, self-adapting decremental overdrive pacing, was assessed in patients with clinical ventricular tachyarrhythmias who underwent programmed ventricular stimulation and serial drug testing. The three phases of this study involved a learning/experience phase, followed by intrapatient comparison of decremental overdrive pacing with conventional antitachycardia pacing modalities of overdrive burst ventricular pacing, and diastolic scanning with single (S2) and double (S2S3) ventricular extrastimuli. The final phase involved an intrapatient comparison of automated decremental overdrive pacing with overdrive burst ventricular pacing in patients with ventricular tachycardia (VT) cycle lengths of 280 msec or greater. Decremental overdrive pacing was superior to overdrive burst pacing and diastolic scanning (S2S3 and S2) (83% vs 38%, 50%, 9%) in patients with VT cycle lengths of 280 msec or greater. Automated decremental overdrive pacing as applied in the final phase was the most efficacious modality, terminating 92% of VT episodes compared with 56% for overdrive burst pacing in the same patients.

摘要

一种新的抗心动过速起搏技术——自适应递减超速起搏，在接受程控心室刺激和系列药物测试的临床室性快速性心律失常患者中进行了疗效和安全性评估。本研究的三个阶段包括一个学习/经验阶段，随后是患者自身将递减超速起搏与传统抗心动过速起搏模式（超速猝发心室起搏）以及单（S2）和双（S2S3）心室期外刺激的舒张期扫描进行比较。最后阶段是在室性心动过速（VT）周期长度为280毫秒或更长的患者中，对自动递减超速起搏与超速猝发心室起搏进行患者自身比较。在VT周期长度为280毫秒或更长的患者中，递减超速起搏优于超速猝发起搏和舒张期扫描（S2S3和S2）（83%对38%、50%、9%）。最后阶段应用的自动递减超速起搏是最有效的模式，终止了92%的VT发作，而同一患者中超速猝发起搏的终止率为56%。