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颅内压及其相关参数在小儿重型创伤性脑损伤治疗中的作用。

Intracranial Pressure and Its Related Parameters in the Management of Severe Pediatric Traumatic Brain Injury.

机构信息

Department of Neurosurgery, Dell Medical School, University of Texas at Austin, Austin, TX, USA.

出版信息

Adv Neurobiol. 2024;42:3-19. doi: 10.1007/978-3-031-69832-3_1.

DOI:10.1007/978-3-031-69832-3_1
PMID:39432035
Abstract

There are a number of challenges in the management of acute traumatic brain injuries in children. Beyond their relatively broad age range, which spans neonates to late adolescence, these children may likewise present with coexisting injuries. Thus, their management often necessitates a multidisciplinary team, who coordinate medical/surgical management during their hospitalization in the intensive care unit, as well as specialists in pediatric neurology and rehabilitation during postoperative recovery. Here we address standard of care for acute management, based upon established guidelines and focusing on intracranial pressure, cerebral perfusion pressure, and autoregulation. We also consider the controversies related to monitoring intracranial pressure and methods for sedation and treatment.

摘要

儿童急性创伤性脑损伤的管理存在诸多挑战。除了年龄范围相对较宽(从新生儿到青春期后期)之外,这些儿童还可能同时存在其他损伤。因此,他们的管理通常需要多学科团队,这些团队在他们住院期间的重症监护病房中协调医疗/手术管理,以及儿科神经学和康复方面的专家在术后恢复期间进行协调。在这里,我们根据既定指南讨论急性管理的标准护理,重点关注颅内压、脑灌注压和自动调节。我们还考虑了与颅内压监测相关的争议以及镇静和治疗方法。

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本文引用的文献

1
Neuromonitoring in Children with Traumatic Brain Injury.儿童创伤性脑损伤的神经监测。
Neurocrit Care. 2024 Feb;40(1):147-158. doi: 10.1007/s12028-023-01779-1. Epub 2023 Jun 29.
2
Hypertonic Saline Versus Other Intracranial-Pressure-Lowering Agents for Patients with Acute Traumatic Brain Injury: A Systematic Review and Meta-analysis.高渗盐水与其他降低急性创伤性脑损伤患者颅内压药物的比较:系统评价和荟萃分析。
Neurocrit Care. 2024 Apr;40(2):769-784. doi: 10.1007/s12028-023-01771-9. Epub 2023 Jun 28.
3
Studying Trends of Auto-Regulation in Severe Head Injury in Paediatrics (STARSHIP): protocol to study cerebral autoregulation in a prospective multicentre observational research database study.
研究儿科严重颅脑损伤的自动调节趋势(STARSHIP):一项前瞻性多中心观察性研究数据库研究中研究脑自动调节的方案。
BMJ Open. 2023 Mar 10;13(3):e071800. doi: 10.1136/bmjopen-2023-071800.
4
Acute Effects of Ketamine on Intracranial Pressure in Children With Severe Traumatic Brain Injury.氯胺酮对严重创伤性脑损伤患儿颅内压的急性影响。
Crit Care Med. 2023 May 1;51(5):563-572. doi: 10.1097/CCM.0000000000005806. Epub 2023 Feb 21.
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Cerebral pressure autoregulation and optimal cerebral perfusion pressure during neurocritical care of children with traumatic brain injury.创伤性脑损伤患儿神经重症监护期间的脑压力自动调节与最佳脑灌注压
J Neurosurg Pediatr. 2023 Feb 17;31(5):503-513. doi: 10.3171/2023.1.PEDS22352. Print 2023 May 1.
6
Cerebrovascular Pressure Reactivity Has a Strong and Independent Association With Outcome in Children With Severe Traumatic Brain Injury.脑血管压力反应与儿童严重创伤性脑损伤的预后有很强的独立相关性。
Crit Care Med. 2023 May 1;51(5):573-583. doi: 10.1097/CCM.0000000000005815. Epub 2023 Feb 15.
7
Severe Pediatric Traumatic Brain Injury Treatment Approaches of Pediatric Intensivists in Turkey PICUs: National Survey Results.土耳其儿科重症监护病房中儿科重症医师对儿童严重创伤性脑损伤的治疗方法:全国调查结果
Turk Arch Pediatr. 2022 Jul;57(4):421-427. doi: 10.5152/TurkArchPediatr.2022.21247.
8
Comparative Effectiveness of Diversion of Cerebrospinal Fluid for Children With Severe Traumatic Brain Injury.儿童严重创伤性脑损伤时脑脊液分流术的效果比较。
JAMA Netw Open. 2022 Jul 1;5(7):e2220969. doi: 10.1001/jamanetworkopen.2022.20969.
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Comparison of Intracranial Pressure Measurements Before and After Hypertonic Saline or Mannitol Treatment in Children With Severe Traumatic Brain Injury.比较儿童严重颅脑损伤患者高渗盐水或甘露醇治疗前后的颅内压测量值。
JAMA Netw Open. 2022 Mar 1;5(3):e220891. doi: 10.1001/jamanetworkopen.2022.0891.
10
Functional Short-Term Outcomes and Mortality in Children with Severe Traumatic Brain Injury: Comparing Decompressive Craniectomy and Medical Management.严重创伤性脑损伤儿童的短期功能结局和死亡率:去骨瓣减压术与药物治疗的比较。
J Neurotrauma. 2022 Jul;39(13-14):944-953. doi: 10.1089/neu.2021.0378.